Dr. Jane Hoyt Buckner MD
Rheumatologist | Rheumatology
1100 9th Ave Seattle WA, 98101Rating
5/5
About
Dr. Jane Buckner is a rheumatologist practicing in Seattle, WA. Dr. Buckner specializes in the treatment of musculoskeletal diseases and systematic autoimmune conditions that can affect the bones, muscles or bones. Eventually, if not treated, these illnesses can also impact the skin, eyes, nervous system and internal organs. Dr. Buckner treats diseases similar to orthopedists but does not perform surgery. Often times, research is conducted to find potential alternatives for the patients illness.
Education and Training
Johns Hopkins University School of Medicine 1987
Provider Details
Expert Publications
Data provided by the National Library of Medicine- T cell selection and differential activation on structurally related HLA-DR4 ligands.
- Identification of type II collagen peptide 261-273-specific T cell clones in a patient with relapsing polychondritis.
- Use of class II tetramers for identification of CD4+ T cells.
- Differential antigen sensitivity and costimulatory requirements in human Th1 and Th2 antigen-specific CD4+ cells with similar TCR avidity.
- Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells.
- Optimization of human T-cell expansion ex vivo using magnetic beads conjugated with anti-CD3 and Anti-CD28 antibodies.
- Regulating the immune system: the induction of regulatory T cells in the periphery.
- Novel APC-like properties of human NK cells directly regulate T cell activation.
- De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells.
- The heat shock protein Hsp70 enhances antigen-specific proliferation of human CD4+ memory T cells.
- Lineage and signal strength determine the inhibitory effect of transforming growth factor beta1 (TGF-beta1) on human antigen-specific Th1 and Th2 memory cells.
- Mice expressing HLA-DQ6alpha8beta transgenes develop polychondritis spontaneously.
- A haplotype-based analysis of the PTPN22 locus in type 1 diabetes.
- Genetic variation in PTPN22 corresponds to altered function of T and B lymphocytes.
- T cells contain an RNase-insensitive inhibitor of APOBEC3G deaminase activity.
Treatments
- Arthritis
- Lupus
Dr. Jane Hoyt Buckner MD's Practice location
Practice At 1100 9th Ave
1100 9th Ave -Seattle, WA 98101Get Direction
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SWEDISH MEDICAL CENTERl
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500 17TH AVENUE SEATTLE WA 98122