Diet and Nutrition

The Link Between Crohn's Disease and B-12 Deficiency

More about pernicious anemia

Severe or long-lasting pernicious anemia can damage the heart, brain, and other organs in the body. (NIH)

Also, according to the (NIH), an accumulation of unnaturally large red blood cells can clump together in bone marrow- their site of origin. The resultant mass is too large to pass into the blood stream and further complicates the medical crisis.