New Guidelines for Diagnosis and Treatment of Lupus

• ANA test positive (it is positive in 95% cases of lupus, and 5% of general population)
• Anti-dsDNA antibody test
• Anti-Sm
• Antiphospholipid antibody
• Low compliment: C3/C4 or CH50
• Direct Coombs’ test (in the absence of hemolytic anemia)