There are 3 things that I tell my patients: 1) NEVER mix 2 forms of artificial hormone together as this is so bad for your body, it will send you into a tailspin metabolically that may take you months to get out of. 2) NEVER take the Depo shot as the artificial Progesterone in the DepoProvera shot is the cause of increased breast cancer, increased heart attack and increased stroke from the Women’s Health Initiative. And NEVER take the oral form of Provera either. Barrier protection can be used and removed: condoms may be annoying because they can fall off or you have to check the expiration date… but they don’t cause cancer. And using a diaphragm means that you put it in no more than 1hr pre-relations and you have to leave it in for at least 12-24hrs post-relations but it doesn’t cause cancer. NEVER, NEVER, NEVER mix artificial hormones together; it’s a recipe for disaster. Sprintec is a 35microgram birth control pill and it should protect you well, especially if you don’t miss any doses and if you always take your pill close to the same time of day.