“Can local anesthesia cause liver issues?”
I will have surgery under local anesthesia. Can local anesthesia cause liver issues?
7 Answers
Local anesthetic (LA) can cause liver toxicity in very high doses that would never be used by any competent anesthesiologist or surgeon. Prior to liver damage, however, a patient wold get LA toxicity, which is characterized by ringing in the ears, numbness around face, and eventually seizures. We always limit our Xylocaine doses to much less than <4 mg/kg. Max dose given is 300 mg.
Some local anesthetics called amide are metabolized by the liver. Small doses of local anesthetic will not affect the liver that much. It should be safe to use the local anesthetic.
No liver problems, but local anesthetic can cause systemic toxicity if the dose is too high or with intravascular injection
Not really
Yes, it depends on genetics.
Unlikely.
Yes, but it would be extremely rare.
