“Can taking aspirin damage your liver?”
I want to start taking aspirin every day for my heart to make sure it stays healthy. Can taking aspirin damage your liver?
3 Answers
High dose of aspirin causes injury in the liver with an increase in aminotransferase elevation and jaundice. There is a study by Dr. Wajahat Mehal that suggest that aspirin may help to prevent and treat liver damage from non-infectious. Acetaminophens can be used instead of aspirin for patients with liver damage. However, both medications in high doses can cause liver damage. Thank you.
Usually aspirin irritates your stomach and decreases platelet function. You can get ulcers, spit up or pass blood, and have a hard time clotting. Platelets are made in the bone marrow. Tylenol is the one known for liver damage.
RB Thomas, MD
RB Thomas, MD
The literature has the following:
“Geriatric Patients: High-Risk Medication:
Beers Criteria: Aspirin, when used chronically at doses more than 325 mg, is identified in the Beers Criteria as a potentially inappropriate medication to be avoided in patients 65 years and older (unless alternative agents ineffective and patient can receive concomitant gastroprotective agent) due to increased risk of GI bleeding and peptic ulcer disease in older adults in high risk category (eg, older than 75 years of age or receiving concomitant oral/parenteral corticosteroids, anticoagulants, or antiplatelet agents). In addition, when aspirin is used for the primary prevention of cardiovascular disease and colorectal cancer, it should be used with caution in older adults ≥70 years of age due to increased risk for major bleeding and inconclusive evidence for the benefits of use as primary prevention in older adults with cardiovascular risk factors (Beers Criteria [AGS 2019]).”
“Geriatric Patients: High-Risk Medication:
Beers Criteria: Aspirin, when used chronically at doses more than 325 mg, is identified in the Beers Criteria as a potentially inappropriate medication to be avoided in patients 65 years and older (unless alternative agents ineffective and patient can receive concomitant gastroprotective agent) due to increased risk of GI bleeding and peptic ulcer disease in older adults in high risk category (eg, older than 75 years of age or receiving concomitant oral/parenteral corticosteroids, anticoagulants, or antiplatelet agents). In addition, when aspirin is used for the primary prevention of cardiovascular disease and colorectal cancer, it should be used with caution in older adults ≥70 years of age due to increased risk for major bleeding and inconclusive evidence for the benefits of use as primary prevention in older adults with cardiovascular risk factors (Beers Criteria [AGS 2019]).”
