You almost certainly have a pituitary tumor with that history. Sometimes they need to be operated on and sometimes not. At a minimum, you need a CT (or MRI - people argue about which one is best, but they both work) to see the size of the tumor. Cabergoline or bromocriptine are the meds we would put you on the suppress the prolactin and usually stabilize the tumor (and even if it turns out not to be tumor). You have to be on it for a while (longer than a week) and have the dose adjusted until your prolactin level comes down. How much of how you are feeling is related to this or to other life factors, I can't be sure, but it is moderately likely the high prolactin (and other effects from the probable tumor) may be causing the fatigue and other symptoms. Get it checked out. Good l uck Fred Coleman