“My immunoglobulin G subclass 4 level was high at 148 - what does this mean?”
Fatigue, joint pain, tachycardia, gastroparesis, pseudotumor cerebi.
Female | 48 years old
Complaint duration: 5 years
Medications: None
Conditions: Possible connective tissue disease
4 Answers
You may have IG4 related disease. Look up on internet. It does respond well to steroids and Rituxan
You need to see a rheumatologits to determine whether you have IGG4 related autoimmune disease.
The first question I would want to know is what was the reason for the test. One could order IgG subclasses in the evaluation of a suspected immune deficiency state. The most common thing for rheumatologists to order this test would be in the evaluation of suspected IgG for related disease. It is important to know that a small percentage of the otherwise normal population will have an elevated test. Additionally, this test can be elevated in many inflammatory and infectious and allergic disorders. So again, I would want to know why your doctor ordered this test. And then based on the test results and his or her suspicions, further testing may be necessary. The most important point is that many conditions can cause an elevation of this specific test Best wishes
You probably have IgGsubtype4 disorder with high incidence of inflammation in various parts of the body, It is treatable ususally with steroids, although many people require different antiflammatories such as leflutmide, or rituximab. Many perople have pancreatitis.
