“Unable to walk or bare weight on my legs”

I'm sorry to hear about the severe pain and trouble you're experiencing with walking. Given your history of multiple knee replacements, ligament injuries, and recurring MRSA infections, it's crucial to address these symptoms quickly. First, contact your orthopaedic surgeon to check for any complications or new issues related to your surgeries. Since you've had recurring MRSA infections, it's important to rule out any joint or nearby area infections that could be causing your pain.

Additionally, if Motrin isn't providing enough relief, discuss with your doctor about adjusting your pain management plan. Consider working with a physical therapist to help regain strength and mobility, but do this under medical supervision given your current pain levels and medical history. If your symptoms persist or worsen, your doctor might refer you to a pain specialist or rheumatologist for further evaluation and treatment.

There are also a few serious conditions to consider, such as blood clots, which can cause pain and difficulty walking and require immediate medical attention. Bone infections, like osteomyelitis, could be contributing to your severe pain, especially given your MRSA history. An abscess, or a pocket of infection, could also develop in the spine or leg, causing pain and mobility issues. Therefore, it's important to see your healthcare team soon to get these possibilities checked out. They can perform tests to determine the cause of your symptoms and help you start feeling better.

Unfortunately your situation is too complex to be able to give you a good answer just from a few sentences of description. A thorough history and physical exam, as well as some imaging is probably going to be needed. My major concern for you, although it may not be the source of your problem directly, is that it sounds like you have a chronically infected total knee replacement if you have to be on lifelong suppressive antibiotics. Unless there is some major reason why they can't do it, typical treatment for that is to remove the implant, place an antibiotic cement spacer in your knee for 6 weeks while you are on IV antibiotics, then go back in and remove the spacer and put a new knee replacement in. It's a big deal yes, but so is having a chronically infected implant that can infect your bone... As far as your bilateral foot pain and left leg pain, if you say that you can't support yourself then i would make sure you get your lower back looked at to make sure that's not the source. Whenever something shows up

I assume your infection in your left Total Knee.I had a similar patient like you once and during a hospitalization wirer IV antibiotics weren't helping, I offered AKA, Above the knee amputation. Several days later after many talks with her daughter who was an RN, she reluctantly accepted. Within a few days she felt much better as the infection was ruining her overall health and the BKA removed all the infection. And she was thanking me.
Prosthetic technology has advanced so much that it is a good option if there is no Saving your leg. The Gun Smoke scene: Doc, Ya gotta save my leg no longer applies in every case.