“Will there be a drug interaction?”
I took 25mg Meclizine this morning for vertigo. It’s been 12 hours now. Just took 25mg of Benadryl. Is that ok or did I make a mistake and should seek care?
Female | 32 years old
2 Answers
It's okay.
Hi,
Meclizine is an anticholinergic medication commonly used for vertigo (with questionable efficacy), and taken together with diphenhydramine (Benadryl) can have additive effects as they are both anticholinergic drugs, and can inhibit the nervous system. However, meclizine has a half life of 5-6 hours, meaning most of the drug is already out of your system if you took the two drugs 12 hours apart. Therefore, the interaction is likely to be very slight, if at all, and you don't need to seek care about this at this time. Be careful with driving or operating machinery as either of these medications can increase fatigue.
Dr. Prieve
Meclizine is an anticholinergic medication commonly used for vertigo (with questionable efficacy), and taken together with diphenhydramine (Benadryl) can have additive effects as they are both anticholinergic drugs, and can inhibit the nervous system. However, meclizine has a half life of 5-6 hours, meaning most of the drug is already out of your system if you took the two drugs 12 hours apart. Therefore, the interaction is likely to be very slight, if at all, and you don't need to seek care about this at this time. Be careful with driving or operating machinery as either of these medications can increase fatigue.
Dr. Prieve
