Hematologist (Blood Specialist) Questions Hematologist

Atypical Lymphocytes?

I am a 35 year old male in good health. I just received my recent blood work back and there was a comment on the results that noted 'few atypical lymphocytes'. All my results in my CBC panel are within the normal range, except for my platelets. My platelets have been on the lower end my whole life and my mother has the same issue. Over the past three years, the platelet range for me is from 116-135. I spoke with my doctor the other day and he was not concerned at all the comment of a 'few atypical lymphocytes', especially since my absolute lymphocytes are smack dab in the middle of the normal range, and my WBC and hemoglobin are normal. He also mentioned some labs and technicians interpret blood smears differently and that could be the case for this sample.

Should I be at ease after the conversation with my doctor or is this cause for concern?

Male | 35 years old
Complaint duration: 0
Medications: N/a
Conditions: N/a

3 Answers

Hematologist(BloodSpecialist)Hematologist
They will order a Flow Cytometry if the numbers are elevated or just repeat the CBC in 1 month.
I think a hematologist should look at the slide, to see the atypical lymphocytes, to be sure they aren't a problem. They can be seen in viral illnesses, like Mono, and other ones, and are a reaction to the viruses, not a permanent thing. They don't look like blasts, the very immature cells that are the first line in precursors to adult lymphocytes. Blasts, finding too many, and more than one, once in a long while, usually mean the person has acute lymphocytic leukemia. I'm only saying this because an atypical lymph DOES NOT mean that I'm worried about you having this disease.
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I agree with your doctor. A few abnormal lymphocytes could be from a recent infection or just an aggressive tech noting some mild abnormalities. I would repeat your count in 6-12 months.