OB-GYN (Obstetrician-Gynecologist) | Maternal & Fetal Medicine Questions OB-GYN

Pregnancy?

I am a 27 year old female. I did a blood pregnancy test on the 7th of May and it came out positive and on the 8th of May. I did another blood pregnancy test and it came out negative. Since then I've been having pains in my abdomen especially the left part. I last saw my period in April and I am not on any contraceptives neither do I take vitamins. What should I do?

Female | 27 years old
Complaint duration: 11/05/2020
Medications: None
Conditions: None

4 Answers

Whenever you have a positive pregnancy test followed by a negative with pain in your pelvis, ALWAYS follow with a blood pregnancy test called a quantitative HCG which gives you a number of the HCG protein in your bloodstream. This number should double every 48hours, with a fetus able to be seen by ultrasound with an HCG that reaches a level of 5,000. But this increase in HCG doesn’t always mean the pregnancy is in the right place; the correct place is inside the uterus. But another place could be inside the Fallopian tube; this location may still show a doubling of HCG but at a certain point it cannot continue to safely grow and it will rupture the tube because it blows the tube past a safe size. If this happens, you may or may not have pain on the side where the pregnancy is in the tube; but if it ruptures, it can be life-threatening as you may bleed or hemorrhage into your abdomen; this is called an ectopic pregnancy because it occurs where it shouldn’t be.

However, another option is that you were able to start the process of implantation in the uterus with an initial positive pregnancy test; however, the negative test that follows usually means your progesterone levels is too low and cannot maintain a rich enough uterine lining for a pregnancy to grow in. If this continues to happen, that’s called recurrent miscarriage; please check with your doctor as this means you need to supplement with Progesterone and maintain a level of 20; NOT taking progesterone can result in miscarriage but not all doctors believe this to be true so advocate for your health and get your levels done.
If your provider ordered the test you should follow up with the provider.
You need an US to r/o miscarriage.

Sincerely,

Dr. Janice Alexander, RN, MD
Hi,

So, typically, when you do a blood pregnancy test, it is a quantitative hCG test and you would get a number. It is pretty unusual to get a blood pregnancy test that is positive one day and negative the next day. My question is the following: Who ordered the blood test? If it is a doctor, they would typically explain the results. I would think that they would order another quantitative blood pregnancy test.
I hope that this helps.

Warmest Regards,

Joseph A. Adashek, MD FACOG