Dr. John S. Spencer MD
Family Practitioner
1423 N Jefferson Ave Suite B100 Springfield MO, 65802About
Dr. John Spencer is a family practitioner practicing in Springfield, MO. Dr. Spencer specializes in comprehensive health care for people of all ages. In addition to diagnosing and treating illnesses, family practitioners also put focus on preventative care with routine checkups, tests and personalized coaching on how to maintain a healthy lifestyle. Dr. Spencer possesses immense general knowledge on maintaining health and today, family practitioners provide more care for the underserved and rural populations than any other medical specialty.
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Expert Publications
Data provided by the National Library of Medicine- Proteomic approaches to antigen discovery.
- Comparative analysis of B- and T-cell epitopes of Mycobacterium leprae and Mycobacterium tuberculosis culture filtrate protein 10.
- Continued proteomic analysis of Mycobacterium leprae subcellular fractions.
- On the origin of leprosy.
- Postgenomic approach to identify novel Mycobacterium leprae antigens with potential to improve immunodiagnosis of infection.
- Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy.
- Use of protein microarrays to define the humoral immune response in leprosy patients and identification of disease-state-specific antigenic profiles.
- The level of PPD-specific IFN-gamma-producing CD4+ T cells in the blood predicts the in vivo response to PPD.
- XCL1 (lymphotactin) chemokine produced by activated CD8 T cells during the chronic stage of infection with Mycobacterium tuberculosis negatively affects production of IFN-gamma by CD4 T cells and participates in granuloma stability.
- Deciphering the proteomic profile of Mycobacterium leprae cell envelope.
- A new Mycobacterium species causing diffuse lepromatous leprosy.
- From genome-based in silico predictions to ex vivo verification of leprosy diagnosis.
- Comparative genomic and phylogeographic analysis of Mycobacterium leprae.
- A modified synthesis and serological evaluation of neoglycoproteins containing the natural disaccharide of PGL-I from Mycobacterium leprae.
- Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach.
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