Dr. Steven W Pipe MD
Hematologist (Pediatric) | Pediatric Hematology-Oncology
1500 E Medical Center Dr B1 Floor Cancer And Ann Arbor MI, 48109About
Dr. Steven Pipe completed his undergraduate medical training at the University of Toronto, and his pediatric training at McMaster University in Hamilton, Ontario. He came to the University of Michigan ...
Education and Training
Univ of Toronto, Fac of Med, Toronto, Ont, Canada 1989
University Of Toronto Faculty Of Medicine 1989
Board Certification
PediatricsAmerican Board of PediatricsABP
DermatologyAmerican Board of DermatologyABD
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Mannose-dependent endoplasmic reticulum (ER)-Golgi intermediate compartment-53-mediated ER to Golgi trafficking of coagulation factors V and VIII.
- Regulation of factor VIII expression and activity by von Willebrand factor.
- A chamber of hope for hemophilia.
- Hemophilia A mutations associated with 1-stage/2-stage activity discrepancy disrupt protein-protein interactions within the triplicated A domains of thrombin-activated factor VIIIa.
- Inferior vena cavectomy for nonexcisable Wilms' tumor thrombus.
- Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs.
- Neonatal sinovenous thrombosis associated with homozygous thermolabile methylenetetrahydrofolate reductase in both mother and infant.
- Hemophilia A mutations within the factor VIII A2-A3 subunit interface destabilize factor VIIIa and cause one-stage/two-stage activity discrepancy.
- The future of recombinant coagulation factors.
- Tricuspid valve thrombus and pulmonary embolus in an infant with homozygous thermolabile methylenetetrahydrofolate reductase and heterozygous prothrombin G20210A variant.
- LMAN1 is a molecular chaperone for the secretion of coagulation factor VIII.
- Bioengineering of coagulation factor VIII for improved secretion.
- Coagulation factors with improved properties for hemophilia gene therapy.
- New high-technology products for the treatment of haemophilia.
Clinical Trials
Professional Memberships
- Fellow Royal College of Physicians
Fellowships
- Pediatric Hematology/Oncology, University of Michigan Health System 1994
- Pediatric Scientist Development Program, University of Michigan Health System 1997
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