Dr. David M Holtzman MD
Neurologist | Neurology
216 S Kingshighway Blvd Saint Louis MO, 63110Rating
5/5
About
Dr. David Holtzman is a distinguished Neurologist in Saint Louis, MO. Dr. Holtzman specializes in diagnosing, treating, and managing disorders of the brain and nervous system. With expertise in handling complex conditions like epilepsy, multiple sclerosis, and migraines, Dr. Holtzman employs advanced techniques and personalized treatment plans to improve patient outcomes. As a neurologist, Dr. Holtzman is committed to staying abreast of the latest developments in neurological research and therapies.
Education and Training
Northwestern Uniiversity 1985
Northwestern University The Feinberg School of Medicine 1985
Board Certification
Psychiatry and NeurologyAmerican Board of Psychiatry and NeurologyABPN
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning.
- In situ atomic force microscopy study of Alzheimer's beta-amyloid peptide on different substrates: new insights into mechanism of beta-sheet formation.
- In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease.
- Unique lipoproteins secreted by primary astrocytes from wild type, apoE (-/-), and human apoE transgenic mice.
- Role of tissue plasminogen activator receptor LRP in hippocampal long-term potentiation.
- BDNF blocks caspase-3 activation in neonatal hypoxia-ischemia.
- BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway.
- Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-beta deposition in vivo.
- Differences in the Abeta40/Abeta42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype.
- No effect of apolipoprotein E on neuronal cell death due to excitotoxic and apoptotic agents in vitro and neonatal hypoxic ischaemia in vivo.
- BDNF protects against spatial memory deficits following neonatal hypoxia-ischemia.
- Clusterin contributes to caspase-3-independent brain injury following neonatal hypoxia-ischemia.
- Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry.
- Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.
- Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology.
Dr. David M Holtzman MD's Practice location
Practice At 216 S Kingshighway Blvd
216 S Kingshighway Blvd -Saint Louis, MO 63110Get Direction
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4400 CLAYTON AVE SAINT LOUIS MO 63110