Dr. Ralph J Deberardinis MD PHD
Pediatrician
34th & Civic Center Blvd Children's Hospital Philadelphia PA, 19104About
Dr. Ralph Deberardinis is a pediatrician practicing in Philadelphia, PA. Dr. Deberardinis is a doctor who specializes in the health care of children. As a pedicatrician, Dr. Deberardinis diagnoses and treats infections, injuries, diseases and other disorders in children. Pediatricians typically work with infants, children, teenagers and young adults up to age 21. They practice medical care as well as preventative health care. Dr. Deberardinis can oversee and manage the physical, mental and emotional health of their patients.
Education and Training
Univ of Pa Sch of Med, Philadelphia Pa 2000
Perelman School of Medicine at the University of Pennsylvania 1996
Board Certification
Medical GeneticsAmerican Board of Medical GeneticsABMG
PediatricsAmerican Board of PediatricsABP
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Exon shuffling by L1 retrotransposition.
- Analysis of the promoter from an expanding mouse retrotransposon subfamily.
- Determination of L1 retrotransposition kinetics in cultured cells.
- A mouse model of human L1 retrotransposition.
- The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation.
- Autophagy in metazoans: cell survival in the land of plenty.
- Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth.
- The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis.
- Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth.
- Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
- The biology of cancer: metabolic reprogramming fuels cell growth and
- Brick by brick: metabolism and tumor cell growth.
- Is cancer a disease of abnormal cellular metabolism? New angles on an old idea.
- Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling.
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer.
Clinical Trials
Awards
- 2007 CHOP Pediatric Scholars Program & Faculty Honor Roll - - American Soci
- 2011 Damon Runyon Cancer Research Foundation Clinical Investigator Award
- 2008 President's Research Council Distinguished Young Researcher Award
Treatments
- Mitochondrial Disease, Metabolism
Professional Memberships
- Member American Academy of Pediatrics
- Member American Association for Cancer Research
- Member American Society of Human Genetics
- Member Society for Inherited Metabolic Disorders
- Member Society for Pediatrics Research
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Nearby Providers
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