Isabella Grumbach, MD, PhD
Internist
200 Hawkins Dr Iowa City IA, 52242About
Dr. Isabella Grumbach is an internist practicing in Iowa City, IA. Dr. Grumbach specializes in the medical treatment of adults. Internists can act as a primary physician or a consultant to a primary physician. They manage both common and rare diseases. Dr. Grumbach provides comprehensive care and manages treatment with surgeons as well. Internists establish long-term relationships with their patients and incorporate disease prevention and mental health care into their practice.
Education and Training
Ruhr-University Medical School, Bochum, Germany MD 0
Neuroanatomy, Ruhr-University, Bochum, Germany PhD 0
Board Certification
Cardiovascular Disease (Internal Medicine)
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Adenoviruses and enteroviruses as pathogens in myocarditis and dilated cardiomyopathy.
- Activation of the Jak-Stat pathway in cells that exhibit selective sensitivity to the antiviral effects of IFN-beta compared with IFN-alpha.
- Transient induction of cytokine production in human myocardial fibroblasts by coxsackievirus B3.
- Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL-expressing cells.
- The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells.
- Calmodulin kinase II is required for fight or flight sinoatrial node physiology.
- Calmodulin kinase II is required for angiotensin II-mediated vascular smooth muscle hypertrophy.
- CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations.
- Sulpho-N-hydroxysuccinimide activated long chain biotin. A new microtitre plate assay for the determination of its stability at different pH values and its reaction rate with protein bound amino groups.
- The multifunctional Ca2+/calmodulin-dependent kinase II delta (CaMKIIdelta) controls neointima formation after carotid ligation and vascular smooth muscle cell proliferation through cell cycle regulation by p21.
- CaMKII in the cardiovascular system: sensing redox states.
- Oxidized CaMKII causes cardiac sinus node dysfunction in mice.
- Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.
- Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.
- The multifunctional Ca2+/calmodulin-dependent kinase II regulates vascular smooth muscle migration through matrix metalloproteinase 9.
Faculty Titles & Positions
- Interim Chair, Department of Internal Medicine University of Iowa - Present
- Professor of Internal Medicine-Cardiovascular Medicine University of Iowa - Present
Fellowships
- University of Illinois at Chicago Postdoctoral Fellow
- Emory University Cardiovascular Diseases
Isabella Grumbach, MD, PhD's Practice location
University of Iowa Healthcare
200 Hawkins Dr -Iowa City, IA 52242Get Direction
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Nearby Providers
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Dr. Thomas M. O'Dorisio MD200 Hawkins Drive Iowa City Iowa 52242![]()
Daniel Chakos200 Hawkins Dr Iowa City IA 52242![]()
Robert W. Summers200 Hawkins Drive Iowa City Iowa 52242![]()
Dr. Matthew Christian Anderson M.D.200 Hawkins Dr Iowa City IA 52242![]()
Dr. Karyn Marie Shanks MD610 Eastbury Dr Iowa City IA 52245![]()
Dr. Maurice C Champion M.D.2460 Towncrest Dr Iowa City IA 52240
Nearest Hospitals
MERCY MEDICAL CENTER - CEDAR RAPIDSl
701 10TH STREET SE CEDAR RAPIDS IA 52403