Dr. Sanford B Krantz M.D.
Hematologist (Blood Specialist) | Hematology
1310 24th Ave S Nashville TN, 37212About
Dr. Sanford Krantz is a hematology internist practicing in Nashville, TN. Dr. Krantz specializes in cases of suspected blood disorders when a diagnosis is unclear and further medical care is needed. Hematology internists work with other specialists such as surgeons, radiation therapists and gynecologists in order to get a better understanding on the cases. Often, patients are asked to participate in clinical research that could result in more efficient treatment methods.
Education and Training
Univ of Chicago, Pritzker Sch of Med, Chicago Il 1959
University of Chicago Division of the Biological Sciences The Pritzker School of Medicine 1959
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Purification and characterization of protein tyrosine phosphatase PTP-MEG2.
- Stem cell factor increases the expression of FLIP that inhibits IFNgamma -induced apoptosis in human erythroid progenitor cells.
- Specific interaction of protein tyrosine phosphatase-MEG2 with phosphatidylserine.
- Reduction of cell cycle progression in human erythroid progenitor cells treated with tumour necrosis factor alpha occurs with reduced CDK6 and is partially reversed by CDK6 transduction.
- PTP-MEG2 is activated in polycythemia vera erythroid progenitor cells and is required for growth and expansion of erythroid cells.
- In human immature BFU-E tumor necrosis factor-alpha not only downregulates CDK6 but also directly produces apoptosis which is prevented by stem cell factor.
- Increased erythropoiesis in polycythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB.
- Identification of an acquired JAK2 mutation in polycythemia vera.
- Role of tyrosine kinases and phosphatases in polycythemia vera.
- JAK2(V617F): Prevalence in a large Chinese hospital population.
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