Dr. Kim E Nichols M.D.
Hematologist (Pediatric) | Pediatric Hematology-Oncology
34th & Civic Center Blvd Children's Hospital Philadelphia PA, 19104About
Dr. Kim Nichols is a pediatric hematologist practicing in Philadelphia, PA. Dr. Nichols specializes in treating children that have a blood disease or cancer. Such blood diseases include disorders of red blood cells, white blood cells and/or platelets. The types of cancers that Dr. Nichols treats include leukemias, lymphomas and certain tumors. Dr. Nichols can also treat bleeding disorders in children. Pediatric hematologists can be found in childrens hospitals, community hospitals, university medical centers and more.
Education and Training
Duke University School of Medicine 1989
Board Certification
PediatricsAmerican Board of PediatricsABP
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Summary of the 12th Nikolas Symposium dendritic cell differentiation: signals, signaling and functional consequences as clues to possible therapy.
- Enhanced T cell responses due to diacylglycerol kinase zeta deficiency.
- Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation.
- Loss of circulating CD27+ memory B cells and CCR4+ T cells occurring in association with elevated EBV loads in XLP patients surviving primary EBV infection.
- TP53, BRCA1, and BRCA2 tumor suppressor genes are not commonly mutated in survivors of Hodgkin's disease with second primary neoplasms.
- Characteristics and outcomes of children with the Wilms tumor-Aniridia syndrome: a report from the National Wilms Tumor Study Group.
- SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation.
- The adaptor protein SH2D1A regulates signaling through CD150 (SLAM) in B cells.
- Treatment of primary Epstein-Barr virus infection in patients with X-linked lymphoproliferative disease using B-cell-directed therapy.
- SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1.
- Molecular and cellular pathogenesis of X-linked lymphoproliferative disease.
- Regulation of NKT cell development by SAP, the protein defective in XLP.
- Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells.
- Sensitive multistep clinical molecular screening of 180 unrelated individuals with retinoblastoma detects 36 novel mutations in the RB1 gene.
- Expansion of functionally immature transitional B cells is associated with human-immunodeficient states characterized by impaired humoral immunity.
Treatments
- Birth Defects
- Leukemia
- Extra Corporeal Shockwave Therapy
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