Dr. Cheleste Marie Thorpe M.D.
Infectious Disease Specialist | Infectious Disease
750 Washington St Tufts-New England Me Boston MA, 02111About
Dr. Cheleste Thorpe is an infectious disease specialist practicing in Boston, MA. Dr. Thorpe specializes in infections that are difficult to diagnose or unresponsive to treatments, such as HIV or airborne infections from a foreign country. Infectious disease specialists usually work with conditions that are not treatable by a primary physician but it is important to keep contact with the primary physician in order to receive information about the patients history and for deciding which diagnostic tests are appropriate.
Education and Training
Tufts Univ Sch of Med, Boston Ma 1993
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Internal MedicineAmerican Board of Internal MedicineABIM- Infectious Disease
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Expression of the highly polymorphic Cryptosporidium parvum Cpgp40/15 gene in genotype I and II isolates.
- Shiga toxin interactions with the intestinal epithelium.
- Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells.
- Shiga toxin-producing Escherichia coli infection.
- AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP.
- The emerging clinical importance of non-O157 Shiga toxin-producing Escherichia coli.
- Clathrin-dependent trafficking of subtilase cytotoxin, a novel AB5 toxin that targets the endoplasmic reticulum chaperone BiP.
- ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression.
- Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways.
- Prevalence of the operon encoding subtilase cytotoxin in non-O157 Shiga toxin-producing Escherichia coli isolated from humans in the United States.
- Shiga toxin-producing Escherichia coli infection in South India.
- Shiga toxin 2 and flagellin from shiga-toxigenic Escherichia coli superinduce interleukin-8 through synergistic effects on host stress-activated protein kinase activation.
- Tissue factor–dependent procoagulant activity of subtilase cytotoxin, a potent AB5 toxin produced by shiga toxigenic Escherichia coli.
- Ricin and Shiga toxins: effects on host cell signal transduction.
- Role of lipid rafts and flagellin in invasion of colonic epithelial cells by Shiga-toxigenic Escherichia coli O113:H21.
Awards
- 2009-2010
- 2007 Teaching Excellence Award from Geographic Medicine and Infectious Dis
- 2000 Oliver Smith Award (recognizes excellence, compassion and service in
- Tufts Medical Center 1999 Oliver Smith AWard
- 1999 Maxwell Finland Young Investigator Award of the Massachusetts Infecti
- 1993 American Medical Women's Association Achievement Citation
- Tufts University School of Medicine 1993 Hewlett-Packard Award
- Tufts University School of Medicine 1992 Alpha Omega Alpha Honor Society
- Branstrom Award, 1983 University of Michigan
- Freshman Scholar, 1983 University of Michigan
Fellowships
- Tufts Medical Center, Fellow 1995
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