Dr. William Morrissey Pardridge M.D.
Internist
1180 Tellem Dr Pacific Palisades CA, 90272About
Dr. William Pardridge is an internist practicing in Pacific Palisades, CA. Dr. Pardridge specializes in the medical treatment of adults. Internists can act as a primary physician or a consultant to a primary physician. They manage both common and rare diseases. Dr. Pardridge provides comprehensive care and manages treatment with surgeons as well. Internists establish long-term relationships with their patients and incorporate disease prevention and mental health care into their practice.
Education and Training
Pennsylvania State University College of Medicine 1976
Provider Details
Expert Publications
Data provided by the National Library of Medicine- P-Glycoprotein on astrocyte foot processes of unfixed isolated human brain capillaries.
- Blood-brain barrier transport of reduced folic acid.
- Epidermal growth factor radiopharmaceuticals: 111In chelation, conjugation to a blood-brain barrier delivery vector via a biotin-polyethylene linker, pharmacokinetics, and in vivo imaging of experimental brain tumors.
- Genetically engineered brain drug delivery vectors: cloning, expression and in vivo application of an anti-transferrin receptor single chain antibody-streptavidin fusion gene and protein.
- An antibody-avidin fusion protein specific for the transferrin receptor serves as a delivery vehicle for effective brain targeting: initial applications in anti-HIV antisense drug delivery to the brain.
- Selective expression of the large neutral amino acid transporter at the blood-brain barrier.
- Blood-brain barrier biology and methodology.
- Imaging brain tumors by targeting peptide radiopharmaceuticals through the blood-brain barrier.
- Targeting rat anti-mouse transferrin receptor monoclonal antibodies through blood-brain barrier in mouse.
- Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain.
- Blood-brain barrier transport of 125I-labeled basic fibroblast growth factor.
- Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor.
- Abeta(1-40) peptide radiopharmaceuticals for brain amyloid imaging: (111)In chelation, conjugation to poly(ethylene glycol)-biotin linkers, and autoradiography with Alzheimer's disease brain sections.
- Noninvasive gene targeting to the brain.
- Selective Lutheran glycoprotein gene expression at the blood-brain barrier in normal brain and in human brain tumors.
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