Paul Cooper Simpson MD
Cardiologist | Cardiovascular Disease
4150 Clement St Va Medical Center 11 San Francisco CA, 94121About
Dr. Paul Simpson is a cardiologist practicing in San Francisco, CA. Dr. Simpson specializes in diagnosing, monitoring, and treating diseases or conditions of the heart and blood vessels and the cardiovascular system. These conditions include heart attacks, heart murmurs, coronary heart disease, and hypertension. Dr. Simpson also practices preventative medicine, helping patients maintain a heart-healthy life.
Education and Training
Washington University in St. Louis School of Medicine 1970
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Knockout of the alpha 1A/C-adrenergic receptor subtype: the alpha 1A/C is expressed in resistance arteries and is required to maintain arterial blood pressure.
- Basal and alpha1-adrenergic-induced activity of minimal rat betaMHC promoters in cardiac myocytes requires multiple TEF-1 but not NFAT binding sites.
- The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse.
- New technique for measurement of left ventricular pressure in conscious mice.
- alpha1A- but not alpha1B-adrenergic receptors precondition the ischemic heart by a staurosporine-sensitive, chelerythrine-insensitive mechanism.
- Both alpha(1A)- and alpha(1B)-adrenergic receptors crosstalk to down regulate beta(1)-ARs in mouse heart: coupling to differential PTX-sensitive pathways.
- Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload.
- Localization of the mouse alpha1A-adrenergic receptor (AR) in the brain: alpha1AAR is expressed in neurons, GABAergic interneurons, and NG2 oligodendrocyte progenitors.
- Left ventricular pressure-volume relationship in conscious mice.
- Isolation and culture of adult mouse cardiac myocytes.
- An alpha1A-adrenergic-extracellular signal-regulated kinase survival signaling pathway in cardiac myocytes.
- Blockade of both alpha1A- and alpha1B-adrenergic receptor subtype signaling is required to inhibit neointimal formation in the mouse femoral artery.
- The alpha-1D Is the predominant alpha-1-adrenergic receptor subtype in human epicardial coronary arteries.
- {alpha}1-Adrenergic receptor subtypes in nonfailing and failing human myocardium.
Treatments
- Heart Disease
- Coronary Artery Disease (cad)
- Pain
- Vascular Disease
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