Michael S Parmacek MD
Cardiologist | Cardiovascular Disease
3400 Spruce St 9035 Gates Philadelphia PA, 19104About
Dr. Michael Parmacek is a cardiologist practicing in Philadelphia, PA. Dr. Parmacek specializes in diagnosing, monitoring, and treating diseases or conditions of the heart and blood vessels and the cardiovascular system. These conditions include heart attacks, heart murmurs, coronary heart disease, and hypertension. Dr. Parmacek also practices preventative medicine, helping patients maintain a heart-healthy life.
Education and Training
Northwestern Uniiversity 1981
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Internal MedicineAmerican Board of Internal MedicineABIM- Cardiovascular Disease- 1987
Provider Details
Expert Publications
Data provided by the National Library of Medicine- The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm.
- Physiological control of smooth muscle-specific gene expression through regulated nuclear translocation of serum response factor.
- Analysis of SM22alpha-deficient mice reveals unanticipated insights into smooth muscle cell differentiation and function.
- Transcriptional programs regulating vascular smooth muscle cell development and differentiation.
- Binding of serum response factor to CArG box sequences is necessary but not sufficient to restrict gene expression to arterial smooth muscle cells.
- Effect of aging on brain respiration and carbohydrate metabolism of Syrian hamsters.
- Perspective: cardiovascular disease in the postgenomic era--lessons learned and challenges ahead.
- SM22beta encodes a lineage-restricted cytoskeletal protein with a unique developmentally regulated pattern of expression.
- Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation.
- Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells.
- Ablation of SM22alpha decreases contractility and actin contents of mouse vascular smooth muscle.
- Myocardin--not quite MyoD.
- Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation.
- Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes.
- GATA-6 regulates genes promoting synthetic functions in vascular smooth muscle cells.
Awards
- 2007 Top Doctors 2007 issue
Treatments
- Nuclear Stress Test (myocardial Perfusion Imaging), Angiogenesis, Cardiac Rehabilitation And More
Professional Memberships
- Fellow American College of Cardiology
- Fellow American College of Physicians
- Member American Federation of Clinical Research
- Member American Heart Association , Abstract Grader, Cardiac Development
- Member American Heart Association , Nominating Committee of the Basic Research Council
- Member American Heart Association Basic Research Council
- Fellow American Heart Association, Council on Basic Cardiovascular Sciences
- Member American Society for Microbiology
- Member Association of American Physicians (AAP) , Elected
- Member Association of Professors of Cardiology
- Member Association of Subspecialty Professors
- Member Association of University Cardiologists
- Member Cardiac Muscle Society
- Member Doris Duke Charitable Foundation , Distinguished Clinical Scientist Review Panel
- Member International Society for Heart Research
- Member Interurban Clinical Society
- Member NIH NHLBI , Scientific Review Group, SCCOR in Pediatric Heart Development and Disease
- Member NIH NHLBI , Cardiovascular Development Study Section, Ad Hoc Reviewer
- Member NIH NHLBI, Board of Scientific Councilors
- Member North American Vascular Biology Organization
- Member Commonwealth of Pennsylvania , Health Research Advisory Committee
- Member John Morgan Society, University of Pennsylvania
- Member Pennsylvania Muscle Institute, University of Pennsylvania
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