Dr. Raghavendra G. Mirmira M.D.
Endocronologist (Pediatric) | Pediatric Endocrinology
702 Barnhill Dr Ri 5960 Indianapolis IN, 46202About
Dr. Raghavendra Mirmira is a pediatric endocrinologist practicing in Indianapolis, IN. Dr. Mirmira specializes in growth, puberty, diabetes or other disorders related to hormones that produce certain conditions in children and growing young adults. Pediatric endocrinologists possess copious knowledge on hormone chemicals and how they can affect other parts of the body and their functions.
Education and Training
University of Chicago Division of the Biological Sciences The Pritzker School of Medicine 1993
Provider Details
Expert Publications
Data provided by the National Library of Medicine- The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter.
- Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains.
- Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1.
- Intramolecular control of transcriptional activity by the NK2-specific domain in NK-2 homeodomain proteins.
- Regulation of the pancreatic pro-endocrine gene neurogenin3.
- Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding.
- Transcription factors direct the development and function of pancreatic beta cells.
- Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells.
- The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1.
- Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes.
- The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.
- The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter.
- Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription.
- Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1.
- Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets.
Treatments
- Diabetes, Type 1 Diabetes (juvenile Diabetes)
- Hyperthyroidism
- Graves' Disease
Dr. Raghavendra G. Mirmira M.D.'s Practice location
Indianapolis, IN 46202Get Direction
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