Dr. Mark J Holterman M.D.
Surgeon (Pediatric) | Pediatric Surgery
1725 W Harrison St Suite 818 Chicago IL, 60612About
Dr. Mark Holterman practices Pediatric Surgery in Chicago, IL. Dr. Holterman treats children who have an illness, injury, or disease that requires surgery. Some of the surgical problems seen by pediatric surgeons are often quite different from those commonly seen by adult or general surgeons. Dr. Holtermandiagnoses, treats, and manages childrens surgical needs such as abnormalities of the groin in childhood and, surgical repair of birth defects, surgical care of tumors, transplantation operations, and endoscopic procedures.
Education and Training
Univ of Va Sch of Med, Charlottesville Va 1988
Board Certification
SurgeryAmerican Board of SurgeryABS- Pediatric Surgery
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Combinatorial search of substituted beta-cyclodextrins for phosphatase-like activity.
- Targeted delivery of anti-CTLA-4 antibody downregulates T cell function in vitro and in vivo.
- Paraneoplastic pemphigus and bronchiolitis obliterans associated with a mediastinal mass: A rare case of Castleman's disease with respiratory failure requiring lung transplantation.
- CD80 (B7-1) and CD86 (B7-2) are functionally equivalent in the initiation and
- Per-6-substituted beta-cyclodextrin libraries inhibit formation of beta-amyloid-peptide (A beta)-derived, soluble oligomers.
- Absence of IL-4, and not suppression of the Th2 response, prevents development of experimental autoimmune Graves' disease.
- CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties.
- Targeted engagement of CTLA-4 prevents autoimmune thyroiditis.
- Selective induction of dendritic cells using granulocyte macrophage-colony stimulating factor, but not fms-like tyrosine kinase receptor 3-ligand, activates thyroglobulin-specific CD4+/CD25+ T cells and suppresses experimental autoimmune thyroiditis.
- Modulation of dendritic cell function and cytokine production to prevent thyroid autoimmunity.
- Targeted CTLA-4 engagement induces CD4+CD25+CTLA-4high T regulatory cells with target (allo)antigen specificity.
- Cardiovascular embryology.
- Electron beam CT scan is a valuable and safe imaging tool for the pediatric surgical patient.
- Enhanced engagement of CTLA-4 induces antigen-specific CD4+CD25+Foxp3+ and CD4+CD25- TGF-beta 1+ adaptive regulatory T cells.
- Preferential costimulation by CD80 results in IL-10-dependent TGF-beta1(+) -adaptive regulatory T cell generation.
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