Dr. John Joseph Osterholzer MD
Pulmonologist | Pulmonary Disease
1500 East Medical Center Dr 3rd Floor Taubman Ct Ann Arbor MI, 48109About
Dr. John Osterholzer practices Pulmonology in Ann Arbor, MI. A pulmonologist is a physician who possesses specialized knowledge and skill in the diagnosis and treatment of pulmonary conditions and diseases. Dr. Osterholzer manages patients who need life support and mechanical ventilation, and is specially trained in diseases and conditions of the chest, particularly pneumonia, asthma, tuberculosis, emphysema, and complicated chest infections.
Education and Training
Univ of Mi Med Sch, Ann Arbor Mi 1999
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Critical Care Medicine
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Role of dendritic cells and alveolar macrophages in regulating early host defense against pulmonary infection with Cryptococcus neoformans.
- Th2 but not Th1 immune bias results in altered lung functions in a murine model of pulmonary Cryptococcus neoformans infection.
- Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia.
- Macrophage dectin-1 expression is controlled by leukotriene B4 via a GM-CSF/PU.1 axis.
- Virulence factors identified by Cryptococcus neoformans mutant screen differentially modulate lung immune responses and brain dissemination.
- FMS-like tyrosine kinase 3 ligand treatment of mice aggravates acute lung injury in response to Streptococcus pneumoniae: role of pneumolysin.
- Interleukin-17A enhances host defense against cryptococcal lung infection through effects mediated by leukocyte recruitment, activation, and gamma interferon production.
- Early or late IL-10 blockade enhances Th1 and Th17 effector responses and promotes fungal clearance in mice with cryptococcal lung infection.
- Role of dendritic cell-pathogen interactions in the immune response to pulmonary cryptococcal infection.
- Local GM-CSF-Dependent Differentiation and Activation of Pulmonary Dendritic Cells and Macrophages Protect against Progressive Cryptococcal Lung Infection in Mice.
- "Scar-cinoma": viewing the fibrotic lung mesenchymal cell in the context of cancer biology.
- Disruption of Early Tumor Necrosis Factor Alpha Signaling Prevents Classical Activation of Dendritic Cells in Lung-Associated Lymph Nodes and Development of Protective Immunity against Cryptococcal Infection.
- Immunoregulation in Fungal Diseases.
- Scavenger Receptor MARCO Orchestrates Early Defenses and Contributes to Fungal Containment during Cryptococcal Infection.
- T Cell-Restricted Notch Signaling Contributes to Pulmonary Th1 and Th2 Immunity during Infection.
Dr. John Joseph Osterholzer MD's Practice location
Practice At 1500 East Medical Center Dr 3rd Floor Taubman Ctr Recp C
1500 East Medical Center Dr 3rd Floor Taubman Ct -Ann Arbor, MI 48109Get Direction
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Nearest Hospitals
UNIVERSITY OF MICHIGAN HEALTH SYSTEMl
1500 E MEDICAL CENTER DRIVE, SPC 5474 ANN ARBOR MI 48109ST JOSEPH MERCY HOSPITALl
5301 E HURON RIVER DR ANN ARBOR MI 48106