Dr. Stanton L Gerson MD
Hematologist-Oncologist | Hematology & Oncology
11100 Euclid Ave Cleveland OH, 44106About
Dr. Stanton Gerson is a hematologist oncologist practicing in Cleveland, OH. Dr. Gerson specializes in the diagnosis, treatment and prevention of blood diseases such as anemia, hemophilia, sickle-cell disease, leukemia and lymphoma. Hematologist Oncologists are also trained in the study of cancer and its attack on other organs.
Education and Training
Harvard Med Sch, Boston Ma 1977
Harvard Medical School 1977
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Hematology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Reduced lung tumorigenesis in human methylguanine DNA--methyltransferase transgenic mice achieved by expression of transgene within the target cell.
- Mesenchymal stem cells: no longer second class marrow citizens.
- Leukocyte O6-alkylguanine-DNA alkyltransferase from human donors is uniformly sensitive to O6-benzylguanine.
- DeltaMGMT-transduced bone marrow infusion increases tolerance to O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea and allows intensive therapy of 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human colon cancer xenografts.
- O6-benzylguanine-resistant mutant MGMT genes improve hematopoietic cell tolerance to alkylating agents.
- Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea.
- Human long-term culture initiating cells are sensitive to benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea and protected after mutant (G156A) methylguanine methyltransferase gene transfer.
- Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.
- Acquired resistance to O6-benzylguanine plus chloroethylnitrosoureas in human breast cancer.
- Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis.
- Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents.
- Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases.
- Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy.
- Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy.
Treatments
- Lymphoma
- Multiple Myeloma
- Leukemia
- Oral Surgery Procedures
- Extra Corporeal Shockwave Therapy
Fellowships
- Medical Oncology - HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA 1983
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