Brian R Rosborough MD, PHD
Internist
Massachusetts General Hospital 55 Fruit Street Boston MA, 02114About
Dr. Brian Rosborough is an internist practicing in Boston, MA. Dr. Rosborough specializes in the medical treatment of adults. Internists can act as a primary physician or a consultant to a primary physician. They manage both common and rare diseases. Dr. Rosborough provides comprehensive care and manages treatment with surgeons as well. Internists establish long-term relationships with their patients and incorporate disease prevention and mental health care into their practice.
Provider Details
Expert Publications
Data provided by the National Library of Medicine- IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.
- Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo.
- IL-27 production and STAT3-dependent upregulation of B7-H1 mediate immune regulatory functions of liver plasmacytoid dendritic cells.
- Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction.
- Regulatory myeloid cells in transplantation.
- Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells.
- A window into immunosuppressant immunoregulation: recipient conversion to rapamycin increases potentially tolerogenic immune cells.
- mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.
- A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells.
- IL-33 exacerbates liver sterile inflammation by amplifying neutrophil extracellular trap formation.
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