Dr. Beverly Shriver Mitchell MD

Fellowships

• University of Michigan Hospital   1977

Publications

• BLOODReduced rR expression and increased rD promoter methylation in CD342012
• JOURL OF BIOLOGICAL CHEMISTRYReactive Oxygen Species Regulate Nucleostemin Oligomerization and Protein Degradation2011
• LEUKEMIA RESEARCHDetermints of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H2008
• Leuk ResGuanine nucleotide depletion inhibits pre-ribosomal R synthesis and causes nucleolar proteins2008
• JOURL OF CLINICAL ONCOLOGYPhase I study of 506U78 administered on a consecutive 5-day schedule in children2005
• JOURL OF CLINICAL ONCOLOGYACCO: ASCO core curriculum outline2005
• LEUKEMIA RESEARCHEffects of the IMP-dehydrogese inhibitor, Tiazofurin2004
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMRole of human Pso4 in mammalian D repair and association with termil deoxynucleotidyl transferase2003
• HaematologicaSequential azacitidine plus lelidomide combition2013
• American jourl of clinical oncologyAge and Genetics: How Do Prognostic Factors at Diagnosis Explain Disparities in Acute Myeloid0
• CANCER CAUSES & CONTROLUnderstanding disparities in leukemia: a tiol study2012
• LEUKEMIASafety, efficacy and biological predictors of response to sequential azacitidine and lelidomide for2012
• HEMATOLOGICAL ONCOLOGYImpact of TET2 mutations on mR expression2011
• Nucleosides, nucleotides & nucleic acidsGuanine nucleotide depletion mediates translocation of nucleolar proteins2008
• Biochem Biophys ActaTescin C interacts with ecto-5'-nucleotidase2008
• JOURL OF BIOLOGICAL CHEMISTRYRegulation of the interaction of inosine monophosphate dehydrogese with mycophenolic acid by GTP2006
• NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDSRegulation of equilibrative nucleoside uptake by protein kise inhibitors2004
• MOLECULAR AND CELLULAR BIOLOGYTargeted disruption of the inosine 5 '-monophosphate dehydrogese type I gene in mice2003
• NEW ENGLAND JOURL OF MEDICINEThe proteasome - An emerging therapeutic target in cancer2003
• JOURL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICSInhibition of nucleoside transport by protein kise inhibitors2003
• JOURL OF CLINICAL ONCOLOGYPhase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic maligncies2002
• AMERICAN JOURL OF HEMATOLOGYClinical course of thrombocytopenia2002
• JOURL OF CLINICAL ONCOLOGYAlemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received2002
• JOURL OF BIOLOGICAL CHEMISTRYInhibition of nucleoside transport by p38 MAPK inhibitors2002
• JOURL OF LABORATORY AND CLINICAL MEDICINECyclosporin A and FK506 decrease adenosine kise activity and adenosine uptake in T-lymphocytes2002
• MOLECULAR AND CELLULAR BIOLOGYAssociation of D polymerase mu (pol mu) with Ku and ligase IV2002
• CANCER RESEARCHArabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kise2002
• CLINICAL CANCER RESEARCHTumor uptake and elimition of 2 '2001
• JOURL OF BIOLOGICAL CHEMISTRYHuman cytosolic 5 '-nucleotidase I - Characterization and role in nucleoside alog resistance2001
• JOURL OF CLINICAL INVESTIGATIONInhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene2000
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMAssociation of termil deoxynucleotidyl transferase with Ku1999
• JOURL OF BIOLOGICAL CHEMISTRYTissue-specific regulation of the ecto1999
• JOURL OF CLINICAL INVESTIGATIONNucleotide pool imbalance1999
• EUROPEAN JOURL OF BIOCHEMISTRYATP and phosphate reciprocally affect subunit association of human recombint High Km 5 '1999
• JOURL OF CLINICAL ONCOLOGYCompound GW506U78 in refractory hematologic maligncies1998
• PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 61Inosine-5 '-monophosphate dehydrogese1998
• JOURL OF BIOLOGICAL CHEMISTRYRegulation of inosine-5'1997
• JOURL OF IMMUNOLOGYAdenosine metabolism during phorbol myristate acetate-mediated induction of HL1997
• JOURL OF BIOLOGICAL CHEMISTRYRegulation of the human inosine monophosphate dehydrogese type I gene1997
• CANCER RESEARCHRetroviral transfer of deoxycytidine kise into tumor cell lines enhances nucleoside toxicity1996
• TURE MEDICINEViral vector transduction of the human deoxycytidine kise cD sensitizes glioma cells to the1996
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMCloning of human adenosine kise cD: Sequence similarity to microbial ribokises and fructokises1996
• ADVANCES IN ENZYME REGULATION, VOL 36Inosine monophosphate dehydrogese expression1996
• Adv Enzyme RegulTranscriptiol regulationof the IMPDH type I and II genes1996
• BIOCHEMICAL PHARMACOLOGYRECOMBINT HUMAN INOSINE MONOPHOSPHATE DEHYDROGESE TYPE-I AND TYPE1995
• MOLECULAR PHARMACOLOGYGTP DEPLETION INDUCED BY IMP DEHYDROGESE INHIBITORS BLOCKS R-PRIMED D-SYNTHESIS1995
• JOURL OF CLINICAL INVESTIGATIONCHARACTERIZATION OF THE DEOXYCYTIDINE KISE PROMOTER IN HUMAN LYMPHOBLAST CELL-LINES1995
• JOURL OF BIOLOGICAL CHEMISTRYCHARACTERIZATION OF THE HUMAN INOSINE-5'-MONOPHOSPHATE DEHYDROGESE TYPE-II GENES1995
• GENOMICSASSIGNMENT OF THE HUMAN TYPE-I IMP DEHYDROGESE GENE (IMPDH1) TO CHROMOSOME 7Q31.3-Q321994
• BLOODHEREDITARY OVEREXPRESSION OF ADENOSINE-DEAMISE IN ERYTHROCYTES1994
• LEUKEMIASTRUCTURAL-ALYSIS OF THE DEOXYCYTIDINE KISE GENE IN PATIENTS WITH ACUTE MYELOID1994
• JOURL OF IMMUNOLOGYEFFECTS OF HUMAN T-LYMPHOCYTE ACTIVATION ON INOSINE MONOPHOSPHATE DEHYDROGESE EXPRESSION1994
• AMERICAN JOURL OF HUMAN GENETICSHEREDITARY OVEREXPRESSION OF ADENOSINE-DEAMISE IN ERYTHROCYTES - EVIDENCE FOR A CIS-ACTING MUTATION1993
• BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONSTYPE-I INOSINE MONOPHOSPHATE DEHYDROGESE - EVIDENCE FOR A SINGLE FUNCTIOL GENE IN MAMMALIAN-SPECIES1993
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMGENOMIC STRUCTURE AND CHROMOSOMAL LOCALIZATION OF THE HUMAN DEOXYCYTIDINE KISE GENE1993
• Mitchell, B. S., Song, J. J., Johnson, E. E., Chen, E., DAYTON, J. S.REGULATION OF HUMAN DEOXYCYTIDINE KISE EXPRESSION1993
• Mitchell, B. S., DAYTON, J. S., Turka, L. A., Thompson, C. B.IMP DEHYDROGESE INHIBITORS AS IMMUNOMODULATORS1993
• JOURL OF CLINICAL INVESTIGATIONGUANINE RIBONUCLEOTIDE DEPLETION INHIBITS T-CELL ACTIVATION1991
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMCLONING AND EXPRESSION OF HUMAN DEOXYCYTIDINE KISE CD1991
• Altertive Methods in ToxicologyDevelopment of an in vitro model system to study the physiologic effects1991
• BLOODERYTHROCYTE ADENOSINE-DEAMISE OVERPRODUCTION IN HEREDITARY HEMOLYTIC-ANEMIA1989
• JOURL OF BIOLOGICAL CHEMISTRYKINETIC-PROPERTIES AND INHIBITION OF HUMAN LYMPHOBLAST-T DEOXYCYTIDINE KISE1989
• BIOCHEMISTRYHUMAN T-LYMPHOBLAST DEOXYCYTIDINE KISE - PURIFICATION AND PROPERTIES1989
• Advances in experimental medicine and biologyProperties of highly purified human T lymphoblast (MOLT-4) deoxycytidine kise.1989
• Nucl Acids ResIdentification of an Apa I polymorphism within the human adenosine deamise gene1989
• Progress in clinical and biological researchErythrocyte-specific overproduction of adenosine deamise: molecular genetic studies.1989
• Advances in experimental medicine and biologyAutosomal domint hemolytic anemia and adenosine deamise overproduction.1989
• BLOODGENETIC EXPRESSION OF ADENOSINE-DEAMISE IN HUMAN LYMPHOID MALIGNCIES1987
• JOURL OF BIOLOGICAL CHEMISTRYTRANSCRIPTIOL REGULATION OF THE C-MYC PROTOONCOGENE BY 11987
• JOURL OF CLINICAL INVESTIGATIONELEVATED ADENOSINE-DEAMISE ACTIVITY AND HEREDITARY HEMOLYTIC1987
• J Clin InvestMolecular basis for elevated adenosine deamise activity in a kindred with hemolytic anemia1987
• JOURL OF CLINICAL INVESTIGATIONZ-NUCLEOTIDE ACCUMULATION IN ERYTHROCYTES FROM LESCH-NYHAN PATIENTS1985
• ANLS OF THE NEW YORK ACADEMY OF SCIENCESBIOCHEMICAL CONSEQUENCES OF ADENOSINE-DEAMISE INHIBITION INVIVO1985
• BRITISH JOURL OF HAEMATOLOGYDIFFERENTIAL METABOLISM OF DEOXYRIBONUCLEOSIDES BY LEUKEMIC T1985
• JOURL OF CLINICAL INVESTIGATION2'-DEOXYGUANOSINE TOXICITY FOR B1984
• JOURL OF LABORATORY AND CLINICAL MEDICINEPURINE METABOLIZING ENZYMES AS PREDICTORS OF LYMPHOBLAST SENSITIVITY TO DEOXYADENOSINE1984
• JOURL OF CLINICAL INVESTIGATIONADENOSINE-DEAMISE DEFICIENCY WITH NORMAL IMMUNE FUNCTION - AN ACIDIC ENZYME MUTATION1983
• Med Gr RoundsDeficiencies of adenosine deamise and purine nucleoside phosphorylase1982
• BLOODINHIBITION OF ADENOSINE-DEAMISE ACTIVITY RESULTS IN CYTO-TOXICITY TO T-LYMPHOBLASTS INVIVO1980
• ANLS OF INTERL MEDICINEPURINOGENIC IMMUNODEFICIENCY DISEASES - CLINICAL-FEATURES AND MOLECULAR MECHANISMS1980
• MEDICAL CLINICS OF NORTH AMERICAMULTIPLE-MYELOMA - CURRENT CONCEPTS IN DIAGNOSIS AND MAGEMENT1980
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMATP DEPLETION AS A CONSEQUENCE OF ADENOSINE-DEAMISE INHIBITION IN MAN1980
• Advances in experimental medicine and biologyTreatment of acute lymphoblastic leukemia with the adenosine deamise inhibitor 2'-deoxycoformycin.1979
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMBIOCHEMICAL BASIS FOR DIFFERENTIAL DEOXYADENOSINE TOXICITY TO LYMPHOBLAST-T AND LYMPHOBLAST1979
• JOURL OF CLINICAL INVESTIGATIONPURINOGENIC IMMUNODEFICIENCY DISEASES1979
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMPURINOGENIC IMMUNODEFICIENCY DISEASES - SELECTIVE TOXICITY OF DEOXYRIBONUCLEOSIDES FOR T-CELLS1978
• In Erythropoiesis, kao K, Fisher J, Pakaku F (Eds) University Park PreGranulocyte and erythroid colony forming cells from rat marrow0
• Proc t Acad Sci (USA)Reversal of UDP-galactose 4-epimerase deficiency of human leukocytes in culture1975
• JOURL OF THE TIOL CANCER INSTITUTEEPIDEMIOLOGICAL ASPECTS OF NEOPLASTIC DISORDERS IN ISRAELI MIGRANT POPULATION .V. LYMPHOMAS1969
• ACTA CYTOLOGICASEX CHROMATIN DETERMITIONS IN SELECTED CASES OF DEVELOPMENTAL SEX ABNORMALITIES1963
• BLOODReduced rRNA expression and increased rDNA promoter methylation in CD342012
• LEUKEMIAEffect of nucleophosmin1 haploinsufficiency on hematopoietic stem cells2012
• MOLECULAR PHARMACOLOGYCyclopentenyl Cytosine Induces Senescence2011
• JOURNAL OF BIOLOGICAL CHEMISTRYReactive Oxygen Species Regulate Nucleostemin Oligomerization and Protein Degradation2011
• CANCER RESEARCHDepletion of Guanine Nucleotides Leads to the Mdm22009
• LEUKEMIA RESEARCHDeterminants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H2008
• Leuk ResGuanine nucleotide depletion inhibits pre-ribosomal RNA synthesis and causes nucleolar proteins2008
• PHARMACOLOGY & THERAPEUTICSThe 5 '-nucleotidases as regulators of nucleotide and drug metabolism2005
• JOURNAL OF CLINICAL ONCOLOGYPhase I study of 506U78 administered on a consecutive 5-day schedule in children2005
• BLOODSynergy between imatinib2005
• BLOODPhase 1 trial of the proteasome inhibitor bortezomib2005
• JOURNAL OF CLINICAL ONCOLOGYACCO: ASCO core curriculum outline2005
• LEUKEMIA RESEARCHEffects of the IMP-dehydrogenase inhibitor, Tiazofurin2004
• CLINICAL CANCER RESEARCHRole of estrogen receptor in the regulation of ecto-5 '-nucleotidase and adenosine in breast cancer2004
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES ORole of human Pso4 in mammalian DNA repair2003
• LEUKEMIARole of cysteine 288 in nucleophosmin cytoplasmic mutations2013
• HaematologicaSequential azacitidine plus lenalidomide combination2013
• American journal of clinical oncologyAge and Genetics: How Do Prognostic Factors at Diagnosis Explain Disparities in Acute Myeloid0
• CANCER CAUSES & CONTROLUnderstanding disparities in leukemia: a national study2012
• LEUKEMIASafety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide2012
• MOLECULAR IMAGING AND BIOLOGYSynthesis of 2 '-Deoxy-2 '-[F-18]Fluoro-9-beta-D-Arabinofuranosylguanine2011
• HEMATOLOGICAL ONCOLOGYImpact of TET2 mutations on mRNA expression2011
• Nucleosides, nucleotides & nucleic acidsGuanine nucleotide depletion mediates translocation of nucleolar proteins2008
• Biochem Biophys ActaTenascin C interacts with ecto-5'-nucleotidase2008
• BLOODNelarabine induces complete remissions in adults with relapsed or refractory T2007
• BloodNelarabing induces complete remissions in adults with relapsed or refractory t2007
• LEUKEMIA RESEARCHEffect of lysophosphatidic acid acyltransferase-beta inhibition in acute leukemia2006
• JOURNAL OF BIOLOGICAL CHEMISTRYRegulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic acid by GTP2006
• Leu ResEffect of lysosphatidic acid acyltransferase-B inhibition in acute luekemia2006
• NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDSRegulation of equilibrative nucleoside uptake by protein kinase inhibitors2004
• HUMAN MOLECULAR GENETICSOn the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa2004
• MOLECULAR AND CELLULAR BIOLOGYTargeted disruption of the inosine 5 '-monophosphate dehydrogenase type I gene in mice2003
• NEW ENGLAND JOURNAL OF MEDICINEThe proteasome - An emerging therapeutic target in cancer2003
• BLOODInduction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion2003
• JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICSInhibition of nucleoside transport by protein kinase inhibitors2003
• JOURNAL OF CLINICAL ONCOLOGYPhase I trial of the proteasome inhibitor PS2002
• AMERICAN JOURNAL OF HEMATOLOGYClinical course of thrombocytopenia2002
• JOURNAL OF CLINICAL ONCOLOGYAlemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received2002
• MOLECULAR PHARMACOLOGYA77 1726 induces differentiation of human myeloid leukemia K562 cells by depletion2002
• JOURNAL OF BIOLOGICAL CHEMISTRYInhibition of nucleoside transport by p38 MAPK inhibitors2002
• JOURNAL OF LABORATORY AND CLINICAL MEDICINECyclosporin A and FK506 decrease adenosine kinase activity and adenosine uptake in T-lymphocytes2002
• MOLECULAR AND CELLULAR BIOLOGYAssociation of DNA polymerase mu (pol mu) with Ku and ligase IV2002
• CANCER RESEARCHArabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase2002
• CLINICAL CANCER RESEARCHTumor uptake and elimination of 2 '2001
• JOURNAL OF BIOLOGICAL CHEMISTRYHuman cytosolic 5 '-nucleotidase I - Characterization and role in nucleoside analog resistance2001
• JOURNAL OF CLINICAL INVESTIGATIONInhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene2000
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OAssociation of terminal deoxynucleotidyl transferase with Ku1999
• JOURNAL OF BIOLOGICAL CHEMISTRYTissue-specific regulation of the ecto1999
• JOURNAL OF CLINICAL INVESTIGATIONNucleotide pool imbalance1999
• EUROPEAN JOURNAL OF BIOCHEMISTRYATP and phosphate reciprocally affect subunit association of human recombinant High Km 5 '1999
• HISTOLOGY AND HISTOPATHOLOGYThe use of the lectin Helix pomatia agglutinin1999
• JOURNAL OF CLINICAL ONCOLOGYCompound GW506U78 in refractory hematologic malignancies1998
• ACTA HISTOCHEMICALectin histochemistry of human leukaemic mast cells1998
• BloodEffects of guanine nucleotide depletion on cell cycle progression in human T lymphocytes1998
• PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 61Inosine-5 '-monophosphate dehydrogenase1998
• JOURNAL OF BIOLOGICAL CHEMISTRYRegulation of inosine-5'1997
• PHARMACEUTICAL RESEARCHCellular delivery of nucleoside diphosphates: A prodrug approach1997
• JOURNAL OF IMMUNOLOGYAdenosine metabolism during phorbol myristate acetate-mediated induction of HL1997
• JOURNAL OF BIOLOGICAL CHEMISTRYRegulation of the human inosine monophosphate dehydrogenase type I gene1997
• CANCER RESEARCHRetroviral transfer of deoxycytidine kinase into tumor cell lines enhances nucleoside toxicity1996
• NATURE MEDICINEViral vector transduction of the human deoxycytidine kin1996
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OCloning of human adenosine kinase cDNA1996
• ADVANCES IN ENZYME REGULATION, VOL 36Inosine monophosphate dehydrogenase expression1996
• Adv Enzyme RegulTranscriptional regulationof the IMPDH type I and II genes1996
• J Am Ger SocA 73 year-old woman with anemia and thrombocytopenia1996
• BIOCHEMICAL PHARMACOLOGYRECOMBINANT HUMAN INOSINE MONOPHOSPHATE DEHYDROGENASE TYPE-I AND TYPE1995
• MOLECULAR PHARMACOLOGYGTP DEPLETION INDUCED BY IMP DEHYDROGENASE INHIBITORS BLOCKS RNA-PRIMED DNA-SYNTHESIS1995
• JOURNAL OF CLINICAL INVESTIGATIONCHARACTERIZATION OF THE DEOXYCYTIDINE KINASE PROMOTER IN HUMAN LYMPHOBLAST CELL-LINES1995
• JOURNAL OF BIOLOGICAL CHEMISTRYCHARACTERIZATION OF THE HUMAN INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE TYPE-II GENES1995
• GENOMICSASSIGNMENT OF THE HUMAN TYPE-I IMP DEHYDROGENASE GENE (IMPDH1) TO CHROMOSOME 7Q31.3-Q321994
• BLOODHEREDITARY OVEREXPRESSION OF ADENOSINE-DEAMINASE IN ERYTHROCYTES1994
• LEUKEMIASTRUCTURAL-ANALYSIS OF THE DEOXYCYTIDINE KINASE GENE IN PATIENTS WITH ACUTE MYELOID1994
• JOURNAL OF IMMUNOLOGYEFFECTS OF HUMAN T-LYMPHOCYTE ACTIVATION ON INOSINE MONOPHOSPHATE DEHYDROGENASE EXPRESSION1994
• Spychala, J., Mitchell, B. S.Regulation of low Km (Ecto-) 5'-nucleotidase gene expression in leukemic cells1994
• AMERICAN JOURNAL OF HUMAN GENETICSHEREDITARY OVEREXPRESSION OF ADENOSINE-DEAMINASE IN ERYTHROCYTES1993
• BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONSTYPE-I INOSINE MONOPHOSPHATE DEHYDROGENASE1993
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OGENOMIC STRUCTURE AND CHROMOSOMAL LOCALIZATION OF THE HUMAN DEOXYCYTIDINE KINASE GENE1993
• Mitchell, B. S., Song, J. J., Johnson, E. E., Chen, E., DAYTON, J. S.REGULATION OF HUMAN DEOXYCYTIDINE KINASE EXPRESSION1993
• Mitchell, B. S., DAYTON, J. S., Turka, L. A., Thompson, C. B.IMP DEHYDROGENASE INHIBITORS AS IMMUNOMODULATORS1993
• CANCER RESEARCHRESISTANCE TO 1-BETA1992
• MOLECULAR PHARMACOLOGYCOMPARISON OF THE EFFECTS OF MIZORIBINE WITH THOSE OF AZATHIOPRINE, 6-MERCAPTOPURINE1992
• JOURNAL OF CLINICAL INVESTIGATIONGUANINE RIBONUCLEOTIDE DEPLETION INHIBITS T-CELL ACTIVATION1991
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OCLONING AND EXPRESSION OF HUMAN DEOXYCYTIDINE KINASE CDNA1991
• Advances in experimental medicine and biologyGuanine ribonucleotide depletion inhibits T cell activation.1991
• Alternative Methods in ToxicologyDevelopment of an in vitro model system to study the physiologic effects1991
• BLOODCD11C (LEU-M5) EXPRESSION CHARACTERIZES A B-CELL CHRONIC LYMPHOPROLIFERATIVE DISORDER WITH FEATURES1990
• CANCER RESEARCHMUTATIONS INDUCED AT THE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE LOCUS OF HUMAN T1990
• CANCER RESEARCHDIFFERENTIAL METABOLISM OF 9-BETA-D-ARABINOFURANOSYLGUANINE IN HUMAN-LEUKEMIC CELLS1989
• LEUKEMIAASSOCIATION OF A MATURE B-CELL LEUKEMIA WITH A 4P+ CHROMOSOMAL ABNORMALITY1989
• BLOODERYTHROCYTE ADENOSINE-DEAMINASE OVERPRODUCTION IN HEREDITARY HEMOLYTIC-ANEMIA1989
• JOURNAL OF BIOLOGICAL CHEMISTRYKINETIC-PROPERTIES AND INHIBITION OF HUMAN LYMPHOBLAST-T DEOXYCYTIDINE KINASE1989
• BIOCHEMISTRYHUMAN T-LYMPHOBLAST DEOXYCYTIDINE KINASE - PURIFICATION AND PROPERTIES1989
• Advances in experimental medicine and biologyProperties of highly purified human T lymphoblast (MOLT-4) deoxycytidine kinase.1989
• Nucl Acids ResIdentification of an Apa I polymorphism within the human adenosine deaminase gene1989
• Progress in clinical and biological researchErythrocyte-specific overproduction of adenosine deaminase: molecular genetic studies.1989
• Advances in experimental medicine and biologyAutosomal dominant hemolytic anemia and adenosine deaminase overproduction.1989
• BLOODGENETIC EXPRESSION OF ADENOSINE-DEAMINASE IN HUMAN LYMPHOID MALIGNANCIES1987
• JOURNAL OF BIOLOGICAL CHEMISTRYTRANSCRIPTIONAL REGULATION OF THE C-MYC PROTOONCOGENE BY 11987
• JOURNAL OF CLINICAL INVESTIGATIONELEVATED ADENOSINE-DEAMINASE ACTIVITY AND HEREDITARY HEMOLYTIC1987
• J Clin InvestMolecular basis for elevated adenosine deaminase activity in a kindred with hemolytic anemia1987
• Advances in experimental medicine and biologyCharacterization of arabinosylguanine resistance in a lymphoblastoid cell line.1986
• JOURNAL OF CLINICAL INVESTIGATIONZ-NUCLEOTIDE ACCUMULATION IN ERYTHROCYTES FROM LESCH-NYHAN PATIENTS1985
• ANNALS OF THE NEW YORK ACADEMY OF SCIENCESBIOCHEMICAL CONSEQUENCES OF ADENOSINE-DEAMINASE INHIBITION INVIVO1985
• BRITISH JOURNAL OF HAEMATOLOGYDIFFERENTIAL METABOLISM OF DEOXYRIBONUCLEOSIDES BY LEUKEMIC T1985
• CANCER RESEARCHEFFECTS OF GUANINE RIBONUCLEOTIDE ACCUMULATION ON THE METABOLISM AND CELL-CYCLE OF HUMAN LYMPHOID1985
• Br J HaematDifferential metabolism of deoxyribonucleosides by leukaemic T cells of immature1985
• PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINEDIFFERENTIAL METABOLISM OF GUANINE NUCLEOSIDES BY HUMAN LYMPHOID-CELL LINES1985
• CANCER RESEARCHMETABOLISM AND SELECTIVE CYTO-TOXICITY OF 9-BETA-D-ARABINOFURANOSYLGUANINE IN HUMAN-LYMPHOBLASTS1985
• ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGYPLASMA-MEMBRANE 5'-NUCLEOTIDASE AND OTHER PURINE ENZYMES IN MURINE LYMPHOCYTES1984
• Cancer Treat SympErythrocyte ATP a dATP measurements predict toxicity following 2'-deoxycoformycin therapy1984
• JOURNAL OF CLINICAL INVESTIGATION2'-DEOXYGUANOSINE TOXICITY FOR B1984
• JOURNAL OF LABORATORY AND CLINICAL MEDICINEPURINE METABOLIZING ENZYMES AS PREDICTORS OF LYMPHOBLAST SENSITIVITY TO DEOXYADENOSINE1984
• CANCER RESEARCHALTERATIONS IN ERYTHROCYTE ADENINE-NUCLEOTIDE POOLS RESULTING FROM 2'-DEOXYCOFORMYCIN THERAPY1983
• BLOODDEOXYRIBONUCLEOSIDE TRIPHOSPHATE ACCUMULATION BY LEUKEMIC-CELLS1983
• CANCER RESEARCHS-ADENOSYLHOMOCYSTEINE CATABOLISM AND BASIS FOR ACQUIRED1983
• JOURNAL OF CLINICAL INVESTIGATIONADENOSINE-DEAMINASE DEFICIENCY WITH NORMAL IMMUNE FUNCTION - AN ACIDIC ENZYME MUTATION1983
• Med Gr RoundsDeficiencies of adenosine deaminase and purine nucleoside phosphorylase1982
• The Lancet (Letter)Adult T-cell leukaemia-lymphoma with unusual phenotype1982
• SCIENCEINHIBITION OF PURINE NUCLEOSIDE PHOSPHORYLASE BY 8-AMINOGUANOSINE1981
• BLOODINHIBITION OF ADENOSINE-DEAMINASE ACTIVITY RESULTS IN CYTO-TOXICITY TO T-LYMPHOBLASTS INVIVO1980
• ANNALS OF INTERNAL MEDICINEPURINOGENIC IMMUNODEFICIENCY DISEASES - CLINICAL-FEATURES AND MOLECULAR MECHANISMS1980
• BIOCHEMICAL MEDICINEAN ASSAY OF DEOXYADENOSINE AND ADENOSINE IN HUMAN-PLASMA BY HPLC1980
• MEDICAL CLINICS OF NORTH AMERICAMULTIPLE-MYELOMA - CURRENT CONCEPTS IN DIAGNOSIS AND MANAGEMENT1980
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OATP DEPLETION AS A CONSEQUENCE OF ADENOSINE-DEAMINASE INHIBITION IN MAN1980
• Cancer treatment reportsTreatment of acute lymphoblastic leukemia with 2'-deoxycoformycin1979
• Advances in experimental medicine and biologyTreatment of acute lymphoblastic leukemia with the adenosine deaminase inhibitor 2'1979
• Advances in experimental medicine and biologyMolecular mechanism(s) of deoxyribonucleoside toxicity in T-lymphoblasts.1979
• Advances in experimental medicine and biologyPossible role for 5'1979
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OBIOCHEMICAL BASIS FOR DIFFERENTIAL DEOXYADENOSINE TOXICITY TO LYMPHOBLAST-T AND LYMPHOBLAST1979
• JOURNAL OF CLINICAL INVESTIGATIONPURINOGENIC IMMUNODEFICIENCY DISEASES1979
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OPURINOGENIC IMMUNODEFICIENCY DISEASES - SELECTIVE TOXICITY OF DEOXYRIBONUCLEOSIDES FOR T-CELLS1978
• Helv Paediat ActaUridine diphosphate galactose 4'-epimerase deficiency1976
• In Erythropoiesis, Nakao K, Fisher J, Pakaku F (Eds) University Park PGranulocyte and erythroid colony forming cells from rat marrow0
• Proc Nat Acad Sci (USA)Reversal of UDP-galactose 4-epimerase deficiency of human leukocytes in culture1975
• JOURNAL OF THE NATIONAL CANCER INSTITUTEEPIDEMIOLOGICAL ASPECTS OF NEOPLASTIC DISORDERS IN ISRAELI MIGRANT POPULATION .V. LYMPHOMAS1969
• Biological BulletinThe effect of phenylthiourea on melanogenesis of Fundulus Heteroclitus1966
• ACTA CYTOLOGICASEX CHROMATIN DETERMINATIONS IN SELECTED CASES OF DEVELOPMENTAL SEX ABNORMALITIES WITH AN1963

Dr. Beverly Shriver Mitchell MD's Practice location