Dr. Morton J. Cowan M.D.
Allergist and Immunologist (Pediatric) | Pediatric Allergy/Immunology
505 Parnassus Ave San Francisco CA, 94143About
Dr. Morton J. Cowan is chief of the Allergy, Immunology and Blood and Marrow Transplant Division at UCSF Benioff Children's Hospital San Francisco. He is recognized throughout the world for research i ...
Board Certification
Allergy and ImmunologyAmerican Board of Allergy and ImmunologyABAI
PediatricsAmerican Board of PediatricsABP
DermatologyAmerican Board of DermatologyABD
Provider Details
Expert Publications
Data provided by the National Library of Medicine- A founder mutation in Artemis, an SNM1-like protein, causes SCID in Athabascan-speaking Native Americans.
- Prenatal diagnosis and carrier detection for Athabascan severe combined immunodeficiency disease.
- Multilineage engraftment with minimal graft-versus-host disease following in utero transplantation of S-59 psoralen/ultraviolet a light-treated, sensitized T cells and adult T cell-depleted bone marrow in fetal mice.
- Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation.
- Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression.
- B7.2-/- mature dendritic cells generate T-helper 2 and regulatory T donor cells in fetal mice after in utero allogeneic bone marrow transplantation.
- Processing of 3'-phosphoglycolate-terminated DNA double strand breaks by Artemis nuclease.
- Hematopoietic stem cell transplantation for severe combined immunodeficiency diseases.
- A novel missense RAG-1 mutation results in T-B-NK+ SCID in Athabascan-speaking Dine Indians from the Canadian Northwest Territories.
- Megadose CD34(+) cell grafts improve recovery of T cell engraftment but not B cell immunity in patients with severe combined immunodeficiency disease undergoing haplocompatible nonmyeloablative transplantation.
- A non-leaky Artemis-deficient mouse that accurately models the human severe combined immune deficiency phenotype, including resistance to hematopoietic stem cell transplantation.
- Wiskott-Aldrich syndrome: diagnosis, clinical and laboratory manifestations, and treatment.
- Primary graft failure after umbilical cord blood transplant rescued by parental haplocompatible stem cell transplantation.
- Advancement of pediatric blood and marrow transplantation research in North America: priorities of the Pediatric Blood and Marrow Transplant Consortium.
- Radiosensitive severe combined immunodeficiency disease.
Clinical Trials
Awards
- 2012 San Francisco Super Doctors
Treatments
- Blood And Marrow Transplant, Leukemia, Myelodysplastic Syndromes (mds) And More
Fellowships
- UCSF, Pediatric Allergy Immunology 1979
Dr. Morton J. Cowan M.D.'s Practice location
Practice At 505 Parnassus Ave
505 Parnassus Ave -San Francisco, CA 94143Get Direction
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Nearby Providers
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Dr. Oscar L Frick MD400 Parnassus Ave San Francisco CA 94143![]()
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Dr. Jennifer M. Puck M.D.513 Parnassus Ave San Francisco CA 94143
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