Dr. Jack Wolfe Singer MD
Hematologist-Oncologist | Hematology & Oncology
Harborview Medical Center 325 9th Ave Seattle WA, 98104Rating
5/5
About
Dr. Jack Singer is a hematologist oncologist practicing in Seattle, WA. Dr. Singer specializes in the diagnosis, treatment and prevention of blood diseases such as anemia, hemophilia, sickle-cell disease, leukemia and lymphoma. Hematologist Oncologists are also trained in the study of cancer and its attack on other organs.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Synthesis and in vivo antitumor activity of poly(l-glutamic acid) conjugates of 20S-camptothecin.
- Poly-(L)-glutamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data.
- Lysophosphatidic acid acyltransferase-beta: a novel target for induction of tumour cell apoptosis.
- Inhibition of lysophosphatidic acid acyltransferase beta disrupts proliferative and survival signals in normal cells and induces apoptosis of tumor cells.
- Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors, a novel class of agents, in multiple myeloma.
- Synthesis, SAR, and antitumor properties of diamino-C,N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase-beta.
- Phospholipase C delta-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells.
- Paclitaxel poliglumex (XYOTAX; CT-2103): an intracellularly targeted taxane.
- Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.
- Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.
- Diamino-C,N-diarylpyridine positional isomers as inhibitors of lysophosphatidic acid acyltransferase-beta.
- Paclitaxel poliglumex (XYOTAX, CT-2103): a macromolecular taxane.
- Substrate specificity of lysophosphatidic acid acyltransferase beta -- evidence from membrane and whole cell assays.
- In vitro and in vivo metabolism of paclitaxel poliglumex: identification of metabolites and active proteases.
- Biological and clinical characterization of paclitaxel poliglumex (PPX, CT-2103), a macromolecular polymer-drug conjugate.
Dr. Jack Wolfe Singer MD's Practice location
Practice At Harborview Medical Center 325 9th Ave
Harborview Medical Center 325 9th Ave -Seattle, WA 98104Get Direction
Dr. Jack Wolfe Singer MD's reviews
Write ReviewPatient Experience with Dr. Singer
Recommended Articles
- Treatment Options of Multiple Myeloma
A team led by a consultant haematology specialist takes care of you if you are a multiple myeloma patient. The team discusses your situation and suggests the best treatment for you, but you will finally decide.It may be paramount to compile a list of questions which you will ask the specialist...
![]()
Daughter's Donation Gives Mom with Lymphoma a Fighting ChanceChyanne Ojageer, a 14-year-old teenager from Kissimmee, Florida, became one of the youngest bone marrow donors in the state when she donated her own bone marrow to help save her mother’s life.Neisha Ojageer, never in her wildest dreams thought that her daughter would be the person to save her...
![]()
The Leukemia & Lymphoma Society to Expand Mission Against Blood CancerOn July 19, 2017, the Leukemia & Lymphoma Society, or LLS, proclaimed that they would be expanding their initiative to beat acute myeloid leukemia. Referred to as "Beat AML Master Trial", the project aims to test new and innovative treatments for those suffering from AML. For more information...
![]()
Study Finds 3% of Pediatric Non-Hodgkin Lymphoma Cases Are Transplant RecipientsLymphoma is a blood cancer that affects both children and adults.Lymphoma begins its growth in the lymphatic white blood cells of the lymph system. This system is a major warrior in fighting off infections and diseases. It is part of the body’s immunity team.The lymph system loops throughout the...
![]()
Arizona Firefighters Raise Funds for Lymphoma StairclimbJackson County Fire District #5 partnered with Dutch Bros. Coffee in Phoenix, Arizona to help raise funds for the Leukemia & Lymphoma Society’s Scott Firefighter Stairclimb in Seattle, which took place at the Columbia Center on March 11th, 2018. All of the money raised for the stairclimb go to...
![]()
Black Sabbath's Tony Iommi Discusses Struggles with LymphomaTony Iommi is one of the few rock and roll legends who can say that they fulfilled the industry’s cliché act of getting the band back together. In 2011, the loss of a good friend brought the Black Sabbath guitarist Iommi back into contact with the band’s original lead vocalist, Ozzy Osbourne....
Nearby Providers
![]()
Mrs. Danielle Nance MD921 Terry Ave Seattle WA 98104![]()
Dr. Sheldon Z Goldberg MD515 Minor Ave Seattle WA 98104![]()
Dr. Sharmila Ahmed MD1101 MADISON ST SEATTLE WA 98104![]()
Hannah M Linden OtherHarborview Medical Center Seattle WA 98104![]()
Michaela Tsai Other1221 MADISON ST SEATTLE WA 98104![]()
Dr. Siting S. Chen MD904 7th Ave Seattle WA 98104
Nearest Hospitals
HARBORVIEW MEDICAL CENTERl
325 9TH AVENUE SEATTLE WA 98104SWEDISH MEDICAL CENTERl
747 BROADWAY SEATTLE WA 98122VIRGINIA MASON MEDICAL CENTERl
925 SENECA ST SEATTLE WA 98101