Dr. Douglas M Tollefsen MD
Hematologist (Blood Specialist) | Hematology
4921 Parkview Pl 7th Floor Saint Louis MO, 63110About
Dr. Douglas Tollefsen is a hematology internist practicing in Saint Louis, MO. Dr. Tollefsen specializes in cases of suspected blood disorders when a diagnosis is unclear and further medical care is needed. Hematology internists work with other specialists such as surgeons, radiation therapists and gynecologists in order to get a better understanding on the cases. Often, patients are asked to participate in clinical research that could result in more efficient treatment methods.
Education and Training
Washington Center / School of Medicine 1977
Washington University in St. Louis School of Medicine 1977
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Amino acid residues of heparin cofactor II required for stimulation of thrombin inhibition by sulphated polyanions.
- Thrombin inhibition by HCII in the presence of elastase-cleaved HCII and thrombin-HCII complex.
- Binding of the products of prothrombin activation to human platelets.
- Anticoagulant activities of a monoclonal antibody that binds to exosite II of thrombin.
- Inhibition of human platelet aggregation by monovalent antifibrinogen antibody fragments.
- Binding of exosite ligands to human thrombin. Re-evaluation of allosteric linkage between thrombin exosites I and II.
- Heparin cofactor II inhibits arterial thrombosis after endothelial injury.
- Heparin cofactor II deficiency.
- The contributions of the alpha 2 beta 1 integrin to vascular thrombosis in vivo.
- The interaction of glycosaminoglycans with heparin cofactor II: structure and activity of a high-affinity dermatan sulfate hexasaccharide.
- Molecular interactions between heparin cofactor II and thrombin.
- Does heparin cofactor II modulate atherosclerosis and restenosis?
- Antithrombotic activity of dermatan sulfate in heparin cofactor II-deficient mice.
- Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity.
- Fusion proteins comprising annexin V and Kunitz protease inhibitors are highly potent thrombogenic site-directed anticoagulants.
Clinical Trials
Treatments
- Anemia
Dr. Douglas M Tollefsen MD's Practice location
Practice At 4921 Parkview Pl 7th Floor
4921 Parkview Pl 7th Floor -Saint Louis, MO 63110Get Direction
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Nearest Hospitals
ST LOUIS CHILDRENS HOSPITALl
ONE CHILDRENS PLACE SAINT LOUIS MO 63110SHRINERS HOSPITALS FOR CHILDRENl
4400 CLAYTON AVE SAINT LOUIS MO 63110