Dr. Linda M Boxer M.D.

Fellowships

• Stanford University School of Medicine,Stanford, Ca, United States   1989

Publications

• JAMA : the jourl of the American Medical AssociationClinical interpretation and implications of whole-genome sequencing.2014
• ONCOGENEFunctiol long-range interactions of the IgH 3 ' enhancers with the bcl-2 promoter region in t(142008
• NUCLEIC ACIDS RESEARCHProtein/D arrays identify nitric oxide-regulated cis-element2007
• FASEB jourlTranscription factor gata4 regulates cardiac BCL2 gene expression in vitro and in vivo.2006
• FASEB JOURLTranscription factor GATA4 regulates cardiac BCL2 gene expression in vitro and in vivo2006
• JOURL OF BIOLOGICAL CHEMISTRYRegulatory elements in the immunoglobulin heavy chain gene 3 '-enhancers induce c2005
• CANCER RESEARCHA genome-wide view of the in vitro response to L-asparagise in acute lymphoblastic leukemia2005
• Paz-Priel, I., Cai, D. H., Wang, D. H., Heckman, C. A., Gombart, A. F.C/EBP alpha and C/EBP alpha myeloid oncoproteins inhibit apoptosis and induce bcl-2 via D2004
• JOURL OF NEUROCHEMISTRYNeurotrophin-3 and a CREB-mediated sigling pathway regulate Bcl-2 expression in oligodendrocyte2004
• JOURL OF BIOLOGICAL CHEMISTRYCytokine-mediated down2003
• JOURL OF NEUROCHEMISTRYOxidative stress-mediated down-regulation of bcl-2 promoter in hippocampal neurons2003
• JOURL OF BIOLOGICAL CHEMISTRYImpaired proliferation2002
• JOURL OF BIOLOGICAL CHEMISTRYA myc-associated zinc finger protein2002
• METHODSAllele-specific alysis of transcription factors binding to promoter regions2002
• ONCOGENEThe critical role of the PE21 element in oncostatin M2001
• MOLECULAR BRAIN RESEARCHThe cyclic AMP response element in the Bcl2001
• CANCER RESEARCHMolecular mechanisms of transcriptiol control of bcl-2 and c2001
• EUROPEAN JOURL OF CELL BIOLOGYNerve growth factor-2000
• JOURL OF BIOLOGICAL CHEMISTRYNF-kappa B activity is required for the deregulation of c2000
• JOURL OF BIOLOGICAL CHEMISTRYAkt/protein kise B up-regulates Bcl-2 expression through cAMP-response element-binding protein2000
• JOURL OF BIOLOGICAL CHEMISTRYA-Myb up-regulates bcl-2 through a Cdx binding site in t(14;18) lymphoma cells2000
• JOURL OF BIOLOGICAL CHEMISTRYInsulin-like growth factor1999
• JOURL OF BIOLOGICAL CHEMISTRYp53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor1999
• NUCLEIC ACIDS RESEARCHThe N-termil domain unique to the long form of the Brn1998
• JOURL OF BIOLOGICAL CHEMISTRYBcl-2 transcription from the proximal P2 promoter is activated in neurol cells by the Brn1998
• JOURL OF BIOLOGICAL CHEMISTRYThe WT1 protein is a negative regulator of the normal bcl-2 allele in t(14;18) lymphomas1997
• JOURL OF BIOLOGICAL CHEMISTRYIdentification of the major positive regulators of c1997
• JOURL OF BIOLOGICAL CHEMISTRYCREB proteins function as positive regulators of the translocated bcl-2 allele in t(141996
• JOURL OF BIOLOGICAL CHEMISTRYREPRESSION OF THE C-MYB GENE BY WT1 PROTEIN IN T-CELL AND B-CELL LINES1995
• JOURL OF BIOLOGICAL CHEMISTRYTHE TRANSCRIPTION FACTOR, NM23H21995
• Ji, L., Arcis, M., Boxer, L. M.NF-KAPPA-B SITES FUNCTION AS POSITIVE REGULATORS OF EXPRESSION OF THE TRANSLOCATED C-MYC ALLELE IN1994
• JOURL OF BIOLOGICAL CHEMISTRYACTIVATION OF C-MYC EXPRESSION BY C1994
• ANNUAL REVIEW OF MEDICINETHE ROLE OF ONCOGENES IN HEMATOLOGIC MALIGNCIES1994
• JAMA : the journal of the American Medical AssociationClinical interpretation and implications of whole-genome sequencing.2014
• LEUKEMIAThe immunoglobulin heavy chain gene 3 ' enhancers induce Bcl2 deregulation2011
• ONCOGENEFunctional long-range interactions of the IgH 3 ' enhancers with the bcl-2 promoter region in t(142008
• NUCLEIC ACIDS RESEARCHProtein/DNA arrays identify nitric oxide2007
• ONCOGENEThe immunoglobulin heavy-chain gene 3 ' enhancers deregulate bcl-2 promoter usage in t(142007
• LEUKEMIAActivation of the c-myc p1 promoter in Burkitt's lymphoma by the hs3 immunoglobulin heavy2007
• CHEMBIOCHEMArtificial zinc(II) complexes regulate cell cycle and apoptosis-related genes in tumor cell lines2007
• MOLECULAR AND CELLULAR BIOLOGYRole of the cyclic AMP response element in the bcl-2 promoter in the regulation of endogenous Bcl2006
• FASEB journalTranscription factor gata4 regulates cardiac BCL2 gene expression in vitro and in vivo.2006
• FASEB JOURNALTranscription factor GATA4 regulates cardiac BCL2 gene expression in vitro and in vivo2006
• ONCOGENEOct transcription factors mediate t(142006
• Paz-Priel, I., Cai, D. H., Wang, D. H., Kowalski, J., Blackford, A., LC/EBP alpha and C/EBP alpha myeloid oncoproteins induce Bcl2005
• MOLECULAR CANCER RESEARCHCCAAT/enhancer binding protein alpha2005
• JOURNAL OF BIOLOGICAL CHEMISTRYRegulatory elements in the immunoglobulin heavy chain gene 3 '-enhancers induce c2005
• MOLECULAR AND CELLULAR BIOLOGYHistone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(142005
• CANCER RESEARCHA genome-wide view of the in vitro response to L-asparaginase in acute lymphoblastic leukemia2005
• Paz-Priel, I., Cai, D. H., Wang, D. H., Heckman, C. A., Gombart, A. F.C/EBP alpha and C/EBP alpha myeloid oncoproteins inhibit apoptosis and induce bcl-2 via DNA2004
• JOURNAL OF NEUROCHEMISTRYNeurotrophin-3 and a CREB-mediated signaling pathway regulate Bcl-2 expression in oligodendrocyte2004
• BLOODGene expression patterns associated with recurrent chromosomal translocations2004
• CANCER RESEARCHCritical elements of the immunoglobulin heavy chain gene enhancers2003
• ONCOGENERegulation of Bcl-2 expression by C/EBP in t(14;18) lymphoma cells2003
• JOURNAL OF BIOLOGICAL CHEMISTRYCytokine-mediated down2003
• JOURNAL OF NEUROCHEMISTRYOxidative stress-mediated down-regulation of bcl-2 promoter in hippocampal neurons2003
• JOURNAL OF BIOLOGICAL CHEMISTRYImpaired proliferation2002
• Fine, B. M., Stanulla, M., Schrappe, M., Ho, M. T., HARBOTT, J., BrownIn childhood acute lymphoblastic leukemia, BCR2002
• ONCOGENENF-kappa B activates Bcl-2 expression in t(14;18) lymphoma cells2002
• JOURNAL OF BIOLOGICAL CHEMISTRYA myc-associated zinc finger protein2002
• METHODSAllele-specific analysis of transcription factors binding to promoter regions2002
• ONCOGENEThe critical role of the PE21 element in oncostatin M2001
• Heckman, C. A., Mehew, J. W., Boxer, L. M.The mechanism of bcl-2 activation by NF-kappa B in t(14;18) lymphomas.2001
• ONCOGENETranslocations involving c-myc and c-myc function2001
• MOLECULAR BRAIN RESEARCHThe cyclic AMP response element in the Bcl2001
• CANCER RESEARCHMolecular mechanisms of transcriptional control of bcl-2 and c2001
• EXPERIMENTAL HEMATOLOGYSuppression of apoptosis2001
• ONCOGENENegative regulation of bcl-2 expression by p53 in hematopoietic cells2001
• EUROPEAN JOURNAL OF CELL BIOLOGYNerve growth factor-2000
• Heckman, C. A., Mehew, J. W., Boxer, L. M.Regulation of Bcl-2 expression by NF-kappa B in t(14;18) lymphoma cells.2000
• JOURNAL OF BIOLOGICAL CHEMISTRYNF-kappa B activity is required for the deregulation of c2000
• JOURNAL OF BIOLOGICAL CHEMISTRYAkt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein2000
• JOURNAL OF BIOLOGICAL CHEMISTRYA-Myb up-regulates bcl-2 through a Cdx binding site in t(14;18) lymphoma cells2000
• CELL GROWTH & DIFFERENTIATIONThe expression of p53 tumor suppressor gene in breast cancer cells is down1999
• JOURNAL OF BIOLOGICAL CHEMISTRYInsulin-like growth factor1999
• FEBS LETTERSA zinc-finger transcription factor induced by TGF1999
• JOURNAL OF BIOLOGICAL CHEMISTRYp53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor1999
• NUCLEIC ACIDS RESEARCHActivation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade1999
• Somsouk, L., Heckman, C. A., Mehew, J. W., Kanda, K., Boxer, L. M.An NF-kappa B site in the IgH enhancer deregulates bcl-2 expression in t(14;18) lymphomas.1999
• Kanda, K., Grandchamps, J., Boxer, L. M.An NF-kappa B site in the IgH enhancer deregulates c-myc expression in Burkitt's lymphoma.1998
• NUCLEIC ACIDS RESEARCHThe N-terminal domain unique to the long form of the Brn1998
• JOURNAL OF BIOLOGICAL CHEMISTRYBcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn1998
• JOURNAL OF BIOLOGICAL CHEMISTRYThe WT1 protein is a negative regulator of the normal bcl-2 allele in t(14;18) lymphomas1997
• JOURNAL OF BIOLOGICAL CHEMISTRYIdentification of the major positive regulators of c1997
• MOLECULAR AND CELLULAR BIOLOGYInduction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation1996
• JOURNAL OF BIOLOGICAL CHEMISTRYCREB proteins function as positive regulators of the translocated bcl-2 allele in t(141996
• MOLECULAR AND CELLULAR BIOLOGYIdentification of an inducible regulator of c-myb expression during T-cell activation1996
• JOURNAL OF BIOLOGICAL CHEMISTRYREPRESSION OF THE C-MYB GENE BY WT1 PROTEIN IN T-CELL AND B-CELL LINES1995
• BLOODMYB BINDING-SITES MEDIATE NEGATIVE REGULATION OF C-MYB EXPRESSION IN T-CELL LINES1995
• MOLECULAR AND CELLULAR BIOLOGYPI-1 BINDING-SITES ARE NEGATIVE REGULATORS OF BCL-2 EXPRESSION IN PRE-B CELLS1995
• JOURNAL OF BIOLOGICAL CHEMISTRYTHE TRANSCRIPTION FACTOR, NM23H21995
• MOLECULAR AND CELLULAR BIOLOGYNF-KAPPA-B SITES FUNCTION AS POSITIVE REGULATORS OF EXPRESSION OF THE TRANSLOCATED C-MYC ALLELE IN1994
• Ji, L., Arcinas, M., Boxer, L. M.NF-KAPPA-B SITES FUNCTION AS POSITIVE REGULATORS OF EXPRESSION OF THE TRANSLOCATED C-MYC ALLELE IN1994
• ONCOGENEDIFFERENTIAL PROTEIN-BINDING TO THE C1994
• JOURNAL OF BIOLOGICAL CHEMISTRYACTIVATION OF C-MYC EXPRESSION BY C1994
• ANNUAL REVIEW OF MEDICINETHE ROLE OF ONCOGENES IN HEMATOLOGIC MALIGNANCIES1994

Dr. Linda M Boxer M.D.'s Practice location