Dr. David H Wagner MD
Emergency Physician
250 Hospital Dr Lexington NC, 27292About
Dr. David Wagner practices Emergency Medicine in Lexington, NC. Dr. Wagner assesses patients who seek immediate medical attention at any time of day or night. Emergency Medicine Physicians are trained to efficiently work with each patient and situation no matter how acute or life-threatening. Dr. Wagner examines patients, determines means of testing, diagnoses conditions, and decides the best treatment methods.
Education and Training
Howard University Medical School MD
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes.
- Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery.
- Peripheral CD4loCD40+ auto-aggressive T cell expansion during insulin-dependent diabetes mellitus.
- Re-shaping the T cell repertoire: TCR editing and TCR revision for good and for bad.
- A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes.
- An analytical workflow for investigating cytokine profiles.
- High distribution of CD40 and TRAF2 in Th40 T cell rafts leads to preferential survival of this auto-aggressive population in autoimmunity.
- Disruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T cells promotes diabetes.
- CD40 on NOD CD4 T cells contributes to their activation and pathogenicity.
- CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunity.
- The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation.
- Isolation & characterization of Hoechst(low) CD45(negative) mouse lung mesenchymal stem cells.
- CD40 engagement of CD4+ CD40+ T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance.
- Galectin-9 controls CD40 signaling through a Tim-3 independent mechanism and redirects the cytokine profile of pathogenic T cells in autoimmunity.
- The specific antigen approach in multiple sclerosis: can it ever be enough?
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