Dr. Jack A Ragheb M.D., PH.D.
Pediatrician
10 Center Dr Msc-1857 Bethesda MD, 20892About
Dr. Jack Ragheb is a pediatrician practicing in Bethesda, MD. Dr. Ragheb is a doctor who specializes in the health care of children. As a pedicatrician, Dr. Ragheb diagnoses and treats infections, injuries, diseases and other disorders in children. Pediatricians typically work with infants, children, teenagers and young adults up to age 21. They practice medical care as well as preventative health care. Dr. Ragheb can oversee and manage the physical, mental and emotional health of their patients.
Education and Training
Johns Hopkins Univ Sch of Med, Baltimore Md 1987
Board Certification
Allergy and ImmunologyAmerican Board of Allergy and ImmunologyABAI
PediatricsAmerican Board of PediatricsABP
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Inhibition of human immunodeficiency virus type 1 by Tat/Rev-regulated expression of cytosine deaminase, interferon alpha2, or diphtheria toxin compared with inhibition by transdominant Rev.
- CD28-Mediated regulation of mRNA stability requires sequences within the coding region of the IL-2 mRNA.
- Anergy and cytokine-mediated suppression as distinct superantigen-induced tolerance mechanisms in vivo.
- The destabilization of IL-2 mRNA by a premature stop codon and its differential stabilization by trans-acting inhibitors of protein synthesis do not support a role for active translation in mRNA stability.
- IL-2 receptor blockade inhibits late, but not early, IFN-gamma and CD40 ligand expression in human T cells: disruption of both IL-12-dependent and -independent pathways of IFN-gamma production.
- Selective cytoplasmic translocation of HuR and site-specific binding to the interleukin-2 mRNA are not sufficient for CD28-mediated stabilization of the mRNA.
- Targeted infection of HIV-1 Env expressing cells by HIV(CD4/CXCR4) vectors reveals a potential new rationale for HIV-1 mediated down-modulation of CD4.
- The role of cytokine mRNA stability in the pathogenesis of autoimmune disease.
- The treatment of multifocal choroiditis associated choroidal neovascularization with sirolimus (rapamycin).
- Direct inhibition of CD40L expression can contribute to the clinical efficacy of daclizumab independently of its effects on cell division and Th1/Th2 cytokine production.
- Human CD14hi monocytes and myeloid dendritic cells provide a cell contact-dependent costimulatory signal for early CD40 ligand expression.
- Taking immunogenicity assessment of therapeutic proteins to the next level.
- IL-2 regulates expression of C-MAF in human CD4 T cells.
- The future of protein particle characterization and understanding its potential to diminish the immunogenicity of biopharmaceuticals: a shared perspective.
- The serological evidence in humans supports a negligible risk of zoonotic infection from porcine circovirus type 2.
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