Dr. Marie Colette Defrances MD,PHD
Pathologist | Anatomic Pathology & Clinical Pathology
200 Lothrop St Pittsburgh PA, 15213About
Dr. Marie Defrances is a pathologist practicing in Pittsburgh, PA. Dr. Defrances is a doctor who specializes in the study of bodily fluids and tissues. As a pathologist, Dr. Defrances can help your primary care doctor make a diagnosis about your medical condition. Dr. Defrances may perform a tissue biopsy to determine if a patient has cancer, practice genetic testing, and complete a number of laboratory examinations. Pathologists can also perform autopsies which can determine a persons cause of death and gain information about genetic progression of a disease.
Education and Training
University of Pittsburgh School of Medicine 1997
Provider Details
Expert Publications
Data provided by the National Library of Medicine- The five amino acid-deleted isoform of hepatocyte growth factor promotes carcinogenesis in transgenic mice.
- The repressive function of AP2 transcription factor on the hepatocyte growth factor gene promoter.
- A mechanism of cell survival: sequestration of Fas by the HGF receptor Met.
- The presence of hepatocyte growth factor in the developing rat.
- Patterns of alpha-1-adrenergic receptor expression in regenerating and neoplastic hepatic tissue.
- Localization of hepatocyte growth factor (HGF) gene on human chromosome 7.
- PI3K is negatively regulated by PIK3IP1, a novel p110 interacting protein.
- Lack of Fas antagonism by Met in human fatty liver disease.
- Expression of hepatocyte growth factor mRNA in regenerating rat liver after partial hepatectomy.
- PIK3IP1, a negative regulator of PI3K, suppresses the development of hepatocellular carcinoma.
- Transgenic expression of cyclooxygenase-2 in hepatocytes accelerates endotoxin-induced acute liver failure.
- Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer.
- Identification and partial characterization of receptor binding sites for HGF on rat hepatocytes.
- A hepatocyte growth factor receptor (Met)-insulin receptor hybrid governs hepatic glucose metabolism.
- Inhibition of T-cell activation by PIK3IP1.
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