Dr. David Edward Thurston MD
Orthopedist
5120 Redbud Lane Topeka KS, 66606About
Dr. David Thurston is an orthopaedic surgeon practicing in Topeka, KS. Dr. Thurston specializes in the diagnosis, treatment and rehabilitation of injuries, diseases and disorders of the bodys musculoskeletal system. As an orthopaedic surgeon, Dr. Thurston tends to bones, ligaments, muscles, joints, nerves and tendons. Orthopaedic surgeons can specialize in certain areas like the hand, spine, hip, foot and ankle, shoulder and elbow or the knee.
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Expert Publications
Data provided by the National Library of Medicine- Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c],[1,4]benzodiazepines.
- Nucleic acid targeting: therapeutic strategies for the 21st century.
- Design, synthesis, and evaluation of a novel sequence-selective epoxide-containing DNA cross-linking agent based on the pyrrolo[2, 1-c],[1,4]benzodiazepine system.
- Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c],[1, 4]benzodiazepine and minor-groove-binding oligopyrrole carriers.
- Soft tissue injuries: use of arthrograms to determine ligament injury to the ankle.
- Soft tissue injuries: use of arthrograms to determine ligament injury to the ankle.
- Effect of C2-exo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c],[1,4]benzodiazepines.
- Effect of C2/C3-endo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c],[1,4]benzodiazepines.
- Design and synthesis of novel pyrrolobenzodiazepine (PBD) prodrugs for ADEPT and GDEPT.
- Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity.
- Synthesis of the first example of a C2-C3/C2'-C3'-endo unsaturated pyrrolo[2,1-c],[1,4]benzodiazepine dimer.
- Synthesis and biological evaluation of an N10-Psec substituted pyrrolo[2,1-c],[1,4]benzodiazepine prodrug.
- Synthesis of novel C2-aryl pyrrolobenzodiazepines (PBDs) as potential antitumour agents.
- An expeditious synthesis of cytotoxic pyrroloisoquinoline derivatives. Structure-activity comparative studies with isomeric pyrroloquinolines.
- Synthesis of the first examples of A-C8/C-C2 amide-Linked
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