Dr. Jerrold Michael Olefsky M.D.
Endocrinology-Diabetes | Endocrinology, Diabetes & Metabolism
9500 Gilman Drive Ucsd, Department Of La Jolla CA, 92093About
Dr. Jerrold Olefsky practices Endocrinology in La Jolla, CA. Dr. Olefsky specializes in preventing, diagnosing, and treating diseases related to hormone imbalance, and the bodys glands in the endocrine system. Endocrinologists are trained and certified to treat a variety of conditions, including menopause, diabetes, infertility, and thyroid disorders, among many others. Dr. Olefsky examines patients, determines means of testing, diagnoses, and decides the best treatment methods.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Endocrinology and Metabolism
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance.
- G alpha-q/11 protein plays a key role in insulin-induced glucose transport in 3T3-L1 adipocytes.
- Inhibition of PLC-gamma1 activity converts nerve growth factor from an anti-mitogenic to a mitogenic signal in CHO cells.
- Endothelin-1-induced GLUT4 translocation is mediated via Galpha(q/11) protein and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.
- A comparison of troglitazone and metformin on insulin requirements in euglycemic intensively insulin-treated type 2 diabetic patients.
- Pertussis toxin-sensitive and -insensitive thrombin stimulation of Shc phosphorylation and mitogenesis are mediated through distinct pathways.
- Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency.
- The tumor suppressor PTEN negatively regulates insulin signaling in 3T3-L1 adipocytes.
- Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes.
- The osmotic shock-induced glucose transport pathway in 3T3-L1 adipocytes is mediated by gab-1 and requires Gab-1-associated phosphatidylinositol 3-kinase activity for full activation.
- A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1.
- Metabolic effects of troglitazone therapy in type 2 diabetic, obese, and lean normal subjects.
- Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists.
- PPAR gamma and the treatment of insulin resistance.
- Diabetes. Gene therapy for rats and mice.
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