Dr. Gerald T Nepom MD
Geneticist | Clinical Biochemical Genetics
1201 9th Ave Seattle WA, 98101About
Dr. Gerald Nepom practices Genetic Medicine in Seattle, WA. As a geneticist, Dr. Nepom performs experiments and analyzes data to interpret the inheritance of different traits in patients. A geneticist evaluates, diagnoses, and manages patients? with hereditary conditions or congenital malformations, genetic risk calculations, and mutation analysis. Dr. Nepom carries out studies, tests, and counsels patients with genetic diseases.
Education and Training
Univ of Wa Sch of Med, Seattle Wa 1978
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Impaired binding of a DQ2 and DQ8-binding HSV VP16 peptide to a DQA1*0501/DQB1*0302 trans class II heterodimer.
- MHC-peptide ligand interactions establish a functional threshold for antigen-specific T cell recognition.
- Peptide binding affinity and pH variation establish functional thresholds for activation of HLA-DQ-restricted T cell recognition.
- Immunogenetic analysis suggests different pathogenesis for obese and lean African-Americans with diabetic ketoacidosis.
- Allelic variation in transcription modulates MHC class II expression and function.
- Antigen recognition.
- HLA class I and class II profiles of patients presenting with Sydenham's chorea.
- Gene therapy in the treatment of autoimmune diseases.
- Increased frequency of HLA class II alleles DRB1*0301 and DQB1*0201 in Lambert-Eaton myasthenic syndrome without associated cancer.
- GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65.
- Low-dose streptozotocin induces sustained hyperglycemia in Macaca nemestrina.
- Molecular aspects of HLA class II alphabeta heterodimers associated with IDDM
- Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset.
- The role of the DR4 shared epitope in selection and commitment of autoreactive T cells in rheumatoid arthritis.
- Radioimmunoassay for glutamic acid decarboxylase-65.
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