Dr. Laura M Gorham M.D.
Hospitalist
1405 Shady Ave Pittsburgh PA, 15217About
Dr. Laura Gorham is a hospitalist practicing in Pittsburgh, PA. Dr. Gorham specializes in the comprehensive medical care of hospitalized patients. As a hospitalist, Dr. Gorham manages the clinical problems of hospitalized patients and the acutely ill, while working to improve the performance of the hospital. Dr. Gorham works in collaboration with all of the different doctors that are working with the patient. Hospitalists are involved in the diagnosis, treatment and medical procedures of patients.
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Expert Publications
Data provided by the National Library of Medicine- In vitro and in vivo studies on the metabolism of tirofiban.
- Species and organ differences in first-pass metabolism of the ester prodrug L-751,164 in dogs and monkeys. In vivo and in vitro studies.
- Disposition of L-738,167, a potent and long-acting fibrinogen receptor antagonist, in dogs. Dose-dependent pharmacokinetics.
- Non-peptide glycoprotein IIb/IIIa inhibitors. 17. Design and synthesis of orally active, long-acting non-peptide fibrinogen receptor antagonists.
- In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate.
- In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s.
- Analysis of metabolite kinetics by deconvolution and in vivo-in vitro correlations of metabolite formation rates: studies of fibrinogen receptor antagonist ester prodrugs.
- In vitro and in vivo evaluations of intestinal barriers for the zwitterion L-767,679 and its carboxyl ester prodrug L-775,318. Roles of efflux and metabolism.
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