Alan Chung-kee Cheng M.D.
Cardiologist | Cardiovascular Disease
143 W Franklin St Chapel Hill NC, 27516About
Dr. Cheng earned his bachelor's and medical degree at Emory University in Atlanta. He completed his internship and residency at the University of North Carolina School of Medicine at Chapel Hill, wher ...
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- 2009
Provider Details
Expert Publications
Data provided by the National Library of Medicine- An intuitive approach to measuring protein surface curvature.
- Optimal charges in lead progression: a structure-based neuraminidase case study.
- Structure-based identification of small molecule binding sites using a free energy model.
- Structure-based maximal affinity model predicts small-molecule druggability.
- Structure of the catalytic domain of human polo-like kinase 1.
- N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR.
- Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase.
- Identification of allosteric PIF-pocket ligands for PDK1 using NMR-based fragment screening and 1H-15N TROSY experiments.
- Quinazolin-4-piperidin-4-methyl sulfamide PC-1 inhibitors: alleviating hERG interactions through structure based design.
- The design, synthesis and potential utility of fluorescence probes that target DFG-out conformation of p38alpha for high throughput screening binding assay.
- Analysis of kinase inhibitor selectivity using a thermodynamics-based partition index.
- Enhanced selectivity profile of pyrazole-urea based DFG-out p38alpha inhibitors.
- Fragment based drug discovery: practical implementation based on ¹⁹F NMR spectroscopy.
- Structure- and property-based design of aminooxazoline xanthenes as selective, orally efficacious, and CNS penetrable BACE inhibitors for the treatment of Alzheimer's disease.
Treatments
- Cardiac Imaging
Professional Memberships
- Member ACP-IM
- Member WellStar Medical Group
Publications
- DEVELOPMENTSpontaneous hair cell regeneration in the neotal mouse cochlea in vivo2014
- Proceedings of the tiol Academy of Sciences of the United States of AmTransient, afferent input-dependent2013
- DEVELOPMENTTympanic border cells are Wnt-responsive2013
- PLOS ONEIntegrity and Regeneration of Mechanotransduction Machinery Regulate Aminoglycoside2013
- PloS oneA simple method for purification of vestibular hair cells and non-sensory cells2013
- PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMWnt sigling induces proliferation of sensory precursors in the posttal mouse cochlea2012
- JARO-JOURL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGYDymic Expression of Lgr5, a Wnt Target Gene, in the Developing and Mature Mouse Cochlea2011
- PLOS ONEFunctiol Hair Cell Mechanotransducer Channels Are Required for Aminoglycoside Ototoxicity2011
- Scientific ReportsIntrinsic regenerative potential of murine cochlear supporting cells2011
- Intertiol jourl of otolaryngologyMechanisms of aminoglycoside ototoxicity and targets of hair cell protection.2011
- Jourl of visualized experiments : JoVEIsolating LacZ-expressing cells from mouse inner ear tissues using flow cytometry.2011
- ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERYDecompression of the Orbital Apex An Alterte Approach to Surgical Excision2009
- OTOLARYNGOLOGY-HEAD AND NECK SURGERYSensorineural hearing loss in patients with cystic fibrosis2009
- LARYNGOSCOPEAirway magement in ger Syndrome2009
- INTERTIOL JOURL OF PEDIATRIC OTORHINOLARYNGOLOGYAirway magement in ger Syndrome2008
- AMERICAN JOURL OF OTOLARYNGOLOGYMelanoacanthoma of the exterl auditory cal: a case report and review of the literature2007
- OTOLARYNGOLOGY-HEAD AND NECK SURGERYCerebrospil fluid leak in the neck: A rare complication of glomus vagale excision2006
- Current opinion in otolaryngology & head and neck surgeryMechanisms of hair cell death and protection.2005
- OTOLARYNGOLOGY-HEAD AND NECK SURGERYAuramine orange stain with fluorescence microscopy is a rapid2005
- JARO-JOURL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGYNeomycin-induced hair cell death and rapid regeneration in the lateral line of zebrafish2003
- JARO-JOURL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGYHair cell death in the avian basilar papilla2003
- JOURL OF NEUROSCIENCECaspase activation in hair cells of the mouse utricle exposed to neomycin2002
- INTERTIOL JOURL OF DEVELOPMENTAL NEUROSCIENCEOxidative stress-induced apoptosis of cochlear sensory cells: otoprotective strategies2000
- BRAIN RESEARCHCalpain inhibitors protect auditory sensory cells from hypoxia1999
- AMERICAN JOURL OF ROENTGENOLOGYLATERAL VENTRICULAR EFFACEMENT AS AN ISOLATED SONOGRAPHIC FINDING IN PREMATURE-INFANTS1995
Alan Chung-kee Cheng M.D.'s Practice location
Practice At 148 Bill Carruth Pkwy Suite 100
148 Bill Carruth Pkwy Suite 100 -Hiram, GA 30141Get Direction
Practice At 143 W Franklin St
143 W Franklin St -Chapel Hill, NC 27516Get Direction
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What Is a CPK Lab Test?What is creatine phosphokinase (CPK)?Creatine phosphokinase (CPK) is an enzyme, which is predominantly present in the heart, brain, and skeletal muscles. Converting creatine into phosphate is the main task of this enzyme. The cells of the body then quickly consume or burn this phosphate and use it...
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What Is an Arrhythmia?An arrhythmia is the violations of the frequency, rhythm, and sequence of heart contractions.Why do arrythmias occur?...
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What Are the Triggers of Atrial Fibrillation?What are the Triggers of Atrial Fibrillation?Atrial fibrillation (A-Fib) is a condition that affects the upper chambers of the heart, also known as the atria.In a healthy human heart, the electrical impulses pass through the atria through a contraction to the ventricles and fibers to complete a...
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What is Ischemia?Ischemia refers to the condition in which the muscles of the heart do not get an adequate supply of oxygen. This mostly happens because of reduced blood flow to the cardiac muscles either due to complete blockages or due to a partial block in the blood vessels that carry blood. This condition, also...
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What is the Impact of High Blood Pressure?What is High Blood Pressure?High blood pressure is a condition whereby an individual’s blood vessels become strained due to high pressure by the blood flowing in them. It’s a dangerous condition not because it has any negative side-effects on its own but because of the potential health problems...
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What are the Methods to Lower Cholesterol Levels?Worried about your cholesterol and triglyceride levels? Planning to take another blood test to check on your cholesterol levels? Did you get a warning from your physician regarding elevated levels of triglycerides and LDL (low-density lipoproteins, the ‘bad’ cholesterol) cholesterol in your...
Nearby Providers
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Richard A Krasuski MDDUMC 3012 2301 Erwin Rd. Durham NC 27516
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