Dr. Henry Lauris Paulson MD, PHD
Neurologist | Neurology
1500 East Medical Center Dr 1st Floor Taubman Ct Ann Arbor MI, 48109Rating
5/5
About
Dr. Henry Paulson is a distinguished Neurologist in Ann Arbor, MI. Dr. Paulson specializes in diagnosing, treating, and managing disorders of the brain and nervous system. With expertise in handling complex conditions like epilepsy, multiple sclerosis, and migraines, Dr. Paulson employs advanced techniques and personalized treatment plans to improve patient outcomes. As a neurologist, Dr. Paulson is committed to staying abreast of the latest developments in neurological research and therapies.
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.
- siRNA-mediated gene silencing in vitro and in vivo.
- Diagnostic testing in neurogenetics. Principles, limitations, and ethical considerations.
- Allele-specific silencing of dominant disease genes.
- Toward therapy for DYT1 dystonia: allele-specific silencing of mutant TorsinA.
- Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration.
- Poly-ubiquitin binding by the polyglutamine disease protein ataxin-3 links its normal function to protein surveillance pathways.
- Destabilization of a non-pathological variant of ataxin-3 results in fibrillogenesis via a partially folded intermediate: a model for misfolding in polyglutamine disease.
- Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles.
- Molecular medicine for the brain: silencing of disease genes with RNA interference.
- Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia.
- Caspase-mediated proteolysis of the polyglutamine disease protein ataxin-3.
- RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.
- Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism.
- RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model.
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Practice At 1500 East Medical Center Dr 1st Floor Taubman Ctr Recp C
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UNIVERSITY OF MICHIGAN HEALTH SYSTEMl
1500 E MEDICAL CENTER DRIVE, SPC 5474 ANN ARBOR MI 48109ST JOSEPH MERCY HOSPITALl
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5301 E HURON RIVER DR ANN ARBOR MI 48106