Dr. David Penman Jacobus M.D.
General Practitioner
37 Cleveland Ln Princeton NJ, 08540About
Dr. David Jacobus is a general practitioner practicing in Princeton, NJ. Dr. Jacobus does not specialize in one area of medicine, however provides routine health care services. General practitioners typically have regular, even life-long patients who they provide health care services to. Dr. Jacobus provides services including physical exams, immunizations, and diagnosing and treating multiple illnesses and injuries. General practitioners typically work in private offices and clinics and have staffs of nurses and administators.
Education and Training
Perelman School of Medicine University of Pennsylvania 1953
Perelman School of Medicine at the University of Pennsylvania 1953
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Novel Saccharomyces cerevisiae screen identifies WR99210 analogues that inhibit Mycobacterium tuberculosis dihydrofolate reductase.
- Identification of the optimal third generation antifolate against P. falciparum and P. vivax.
- Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives.
- Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2'-substituted triclosan derivatives.
- X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy.
- Antimalarial pharmacodynamics and pharmacokinetics of a third-generation antifolate--JPC2056--in cynomolgus monkeys using an in vivo in vitro model.
- Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo.
- The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.
- Triclosan derivatives: towards potent inhibitors of drug-sensitive and drug-resistant Mycobacterium tuberculosis.
- Novel diaryl ureas with efficacy in a mouse model of malaria.
- JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial
- Evaluation of the 2-Aminomethylphenol JPC-2997 in Aotus Monkeys Infected with Plasmodium falciparum.
- Lead Selection of a New Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.
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