Dr. Mark H Kaplan MD
Infectious Disease Specialist | Infectious Disease
1051 North Canton Center Rd Canton MI, 48187About
Dr. Mark Kaplan is an infectious disease specialist practicing in Canton, MI. Dr. Kaplan specializes in infections that are difficult to diagnose or unresponsive to treatments, such as HIV or airborne infections from a foreign country. Infectious disease specialists usually work with conditions that are not treatable by a primary physician but it is important to keep contact with the primary physician in order to receive information about the patients history and for deciding which diagnostic tests are appropriate.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Infectious Disease
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.
- Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction.
- The homeostasis but not the differentiation of T cells is regulated by p27(Kip1).
- Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M.
- Neonatal tolerance in the absence of Stat4- and Stat6- dependent Th cell differentiation.
- BATF transgenic mice reveal a role for activator protein-1 in NKT cell development.
- Expression of a constitutively active Stat6 in vivo alters lymphocyte homeostasis with distinct effects in T and B cells.
- STAT4 signal pathways regulate inflammation and airway physiology changes in allergic airway inflammation locally via alteration of chemokines.
- Viral studies on amniotic fluid from fetuses with and without abnormalities detected by prenatal sonography.
- STAT4 requires the N-terminal domain for efficient phosphorylation.
- Distinct requirements for the naturally occurring splice forms Stat4alpha and Stat4beta in IL-12 responses.
- Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines.
- STAT4 is required for interleukin-12-induced chromatin remodeling of the CD25 locus.
- Signal transducer and activator of transcription (Stat)-6-dependent, but not Stat4-dependent, immunity is required for the development of autoimmunity in Graves' hyperthyroidism.
- Cutting edge: induction of the antigen-processing enzyme IFN-gamma-inducible lysosomal thiol reductase in melanoma cells Is STAT1-dependent but CIITA-independent.
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