Dr. Reuben Paul Siraganian M.D.
Allergist and Immunologist | Allergy
National Institutes Of Health Building 49, 1a16 Bethesda MD, 20892About
Dr. Reuben Siraganian practices Allergy and Immunology care in Bethesda, MD. Dr. Siraganian specializes in the diagnosis and treatment of asthma and other allergic diseases. Allergist-Immunologists are trained and certified to treat each patients sensitivity and response to allergens of varying severity. Dr. Siraganian provides several means of testing and treatment to increase immunity to potentially harmful substances.
Education and Training
Suny-Hlth Sci Ctr At Brooklyn, Coll of Med, Brooklyn Ny 1962
Board Certification
Allergy and ImmunologyAmerican Board of Allergy and ImmunologyABAI
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Evidence that the "mouse mastocytoma" cell line (MCT-1) is of rat origin.
- Evidence that the "mouse mastocytoma" cell line (MCT-1) is of rat origin.
- CD45 is essential for Fc epsilon RI signaling by ZAP70, but not Syk, in Syk-negative mast cells.
- Point mutation of a tyrosine in the linker region of Syk results in a gain of function.
- The Src homology 2 domain of Vav is required for its compartmentation to the plasma membrane and activation of c-Jun NH(2)-terminal kinase 1.
- Positive regulation of c-Jun N-terminal kinase and TNF-alpha production but not histamine release by SHP-1 in RBL-2H3 mast cells.
- Regulation of protein kinase CbetaI by two protein-tyrosine kinases, Btk and Syk.
- The NH2-terminal region of focal adhesion kinase reconstitutes high affinity IgE receptor-induced secretion in mast cells.
- Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody.
- Mutant RBL mast cells defective in Fc epsilon RI signaling and lipid raft biosynthesis are reconstituted by activated Rho-family GTPases.
- Identification and isolation of rat bone marrow-derived mast cells using the mast cell-specific monoclonal antibody AA4.
- Activated Cdc42/Rac reconstitutes Fcepsilon RI-mediated Ca2+ mobilization and degranulation in mutant RBL mast cells.
- SH2 domain-mediated targeting, but not localization, of Syk in the plasma membrane is critical for FcepsilonRI signaling.
- Refinements in the automated fluorometric histamine analysis system.
- Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival.
Dr. Reuben Paul Siraganian M.D.'s Practice location
Reuben Siraganian
National Institutes Of Health Building 49, 1a16 -Bethesda, MD 20892Get Direction
Dr. Reuben Paul Siraganian M.D.'s reviews
Write ReviewRecommended Articles
![]()
Steroid Drugs for LupusWhat is Lupus?Lupus is known as a chronic autoimmune medical condition, which tends to damage any part of the body such as the skin, joints, or organs. The type of lupus we're talking about is systemic lupus erythematosus (SLE), which usually lasts for a longer duration from weeks to many years....
![]()
Can Eczema Be Treated with Over-the-Counter Medications?What is eczema?Eczema is a condition that affects the skin. Its typical symptoms include a rough inflamed skin with fluid-filled blisters that are itchy. Eczema most often affects the areas of the neck, inner elbows, behind the knees, the wrists, ankles, and the creases between the buttocks. The...
![]()
What Should I Know About Asthma Inhalers?Inhalers are very popular, lifesaving medications for many who are suffering from asthma and other lung conditions. Knowing about the different types of inhalers and how to use them effectively is very important in controlling the conditions. An asthma inhaler is ideal to deliver the medication for...
![]()
Is Vaccination an Old Method or Another Achievement of the Modern Era?In the early 19th to the 20th century, parents would have been surprised to know that future generations would be free from childhood diseases. Diphtheria was then one of the most common diseases that took the lives of thousands of children, while polio left thousands of children crippled. Measles...
![]()
Is There a Link Between Asthma and Bronchitis?Bronchitis and Asthma are both inflammatory conditions that affect lungs where a person’s airways swell up, causing them breathing problems.Asthma, also known as bronchial asthma, is characterized as a chronic condition in which a person’s airways become inflamed, narrow and swollen, and produce...
![]()
How is Chicken Pox Diagnosed?Chicken pox is a very serious viral disease that results from the varicella zoster virus. The most common sign and indicator of chicken pox is the blistering rash all over one's body. The symptoms are more evident during the cold season, and young children are to be vaccinated against the disease....
Nearby Providers
![]()
Dr. Monica G. Lawrence M.D.10 Center Dr Rm 11d03 Bethesda MD 20892![]()
Dr. Jennifer Woodard Leiding M.D.9000 Rockville Pike Bethesda MD 20892![]()
Dr. Melody Carter M.D.10 Center Dr Msc 1881 Bethesda MD 20892![]()
Dr. Paneez Khoury M.D.50 South Dr Bethesda MD 20892![]()
Dr. Gulbu Uzel MDNih Niaid Lcid 9000 Rockville Pike Bethesda MD 20892![]()
Dr. Henry Clifford Lane M.D.10 Center Drive, Msc 1460 Bethesda MD 20892
Nearest Hospitals
SIBLEY MEMORIAL HOSPITALl
5255 LOUGHBORO RD NW WASHINGTON DC 20016HOLY CROSS HOSPITALl
1500 FOREST GLEN ROAD SILVER SPRING MD 20910SUBURBAN HOSPITALl
8600 OLD GEORGETOWN ROAD BETHESDA MD 20814