Dr. Paul Michael Macdonald M.D.
Internist
6 TSIENNETO RD DERRY NH, 03038About
Dr. Paul Macdonald is an internist practicing in North Billerica, MA. Dr. Macdonald specializes in the medical treatment of adults. Internists can act as a primary physician or a consultant to a primary physician. They manage both common and rare diseases. Dr. Macdonald provides comprehensive care and manages treatment with surgeons as well. Internists establish long-term relationships with their patients and incorporate disease prevention and mental health care into their practice.
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Recognition of a bicoid mRNA localization signal by a protein complex containing Swallow, Nod, and RNA binding proteins.
- Translational control: a cup half full.
- Live imaging of nuage and polar granules: evidence against a precursor-product relationship and a novel role for Oskar in stabilization of polar granule components.
- Localization-dependent oskar protein accumulation; control after the initiation of translation.
- Genetic interactions of Drosophila melanogaster arrest reveal roles for translational repressor Bruno in accumulation of Gurken and activity of Delta.
- Recognition of the bcd mRNA localization signal in Drosophila embryos and ovaries.
- Translational repression by Bicoid: competition for the cap.
- Prediction and verification of microRNA targets by MovingTargets, a highly
- Imp associates with squid and Hrp48 and contributes to localized expression of gurken in the oocyte.
- Oskar controls morphology of polar granules and nuclear bodies in Drosophila.
- A late phase of Oskar accumulation is crucial for posterior patterning of the Drosophila embryo, and is blocked by ectopic expression of Bruno.
- Two distinct domains of Bruno bind specifically to the oskar mRNA.
- Identification of genes that influence gurken expression.
- Bicaudal C and trailer hitch have similar roles in gurken mRNA localization and cytoskeletal organization.
- miRNA-dependent translational repression in the Drosophila ovary.
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