Dr. Michael Owen Dorschner PH.D.
Geneticist | Clinical Molecular Genetics
5755 Cottle Rd Bldg. 6 San Jose CA, 95123About
Dr. Michael Dorschner practices Genetic Medicine in San Jose, CA. As a geneticist, Dr. Dorschner performs experiments and analyzes data to interpret the inheritance of different traits in patients. A geneticist evaluates, diagnoses, and manages patients? with hereditary conditions or congenital malformations, genetic risk calculations, and mutation analysis. Dr. Dorschner carries out studies, tests, and counsels patients with genetic diseases.
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Expert Publications
Data provided by the National Library of Medicine- Comparative analysis of two Nramp loci from rainbow trout.
- High levels of MHC class II allelic diversity in lake trout from Lake Superior.
- Lack of effect of beta-naphthoflavone on induction of Nramp genes in adult rainbow trout Oncorhynchus mykiss.
- Diagnosis of five spinocerebellar ataxia disorders by multiplex amplification and capillary electrophoresis.
- Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse.
- Genome-wide identification of DNaseI hypersensitive sites using active chromatin sequence libraries.
- Genomic context of paralogous recombination hotspots mediating recurrent NF1 region microdeletion.
- Discovery of functional noncoding elements by digital analysis of chromatin structure.
- High-throughput localization of functional elements by quantitative chromatin profiling.
- Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays.
- Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma.
- Comprehensive mapping of long-range interactions reveals folding principles of the human genome.
- CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus.
- Sequencing newly replicated DNA reveals widespread plasticity in human replication timing.
- Gammaretroviral vector integration occurs overwhelmingly within and near DNase hypersensitive sites.
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