Dr. Stephan A Grupp M.D.
Hematologist (Pediatric) | Pediatric Hematology-Oncology
34th & Civic Center Blvd Children's Hospital Philadelphia PA, 19104Rating
5/5
About
As an attending physician in the Cancer Center, the director of Translational Research of the Center for Childhood Cancer Research, and the director of the Stem Cell Laboratory, I take on many roles h ...
Education and Training
Univ of Cincinnati Coll of Med, Cincinnati Oh 1987
University of Cincinnati College of Medicine 1987
Board Certification
DermatologyAmerican Board of DermatologyABD
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Inhibition of tumor growth in a human neuroblastoma xenograft model with TNP-470.
- CD34 selection as a stem cell purging strategy for neuroblastoma: preclinical and clinical studies.
- Rapid-sequence tandem transplant for children with high-risk neuroblastoma.
- The angiogenesis inhibitor tnp-470 effectively inhibits human neuroblastoma xenograft growth, especially in the setting of subclinical disease.
- Angiogenesis inhibitor TNP-470 during bone marrow transplant: safety in a preclinical model.
- Cytoplasmic micro heavy chain confers sensitivity to dexamethasone-induced apoptosis in early B-lineage acute lymphoblastic leukemia.
- Role of the BCR complex in B cell development, activation, and leukemic transformation.
- Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling.
- An unexpectedly high incidence of Epstein-Barr virus lymphoproliferative disease after CD34+ selected autologous peripheral blood stem cell transplant in neuroblastoma.
- Unmasking Evans syndrome: T-cell phenotype and apoptotic response reveal autoimmune lymphoproliferative syndrome (ALPS).
- Safety and efficacy of allogeneic PBSC collection in normal pediatric donors: the pediatric blood and marrow transplant consortium experience (PBMTC) 1996-2003.
- The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL.
- Collection, storage, and infusion of stem cells in children with high-risk neuroblastoma: saving for a rainy day.
- Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS).
- High-risk neuroblastoma treated with tandem autologous peripheral-blood stem cell-supported transplantation: long-term survival update.
Clinical Trials
- Unrelated And Partially Matched Related Donor PSCT w/ TCR ?? Depletion for Patients With BMF
- Study of the Tocilizumab Optimization Timing for CART19 Associated Cytokine Release Syndrome
- Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients
- CD22 Redirected Autologous T Cells for ALL
- A Multi-Center Study Evaluating KTE-C19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
- CD19 CART Long Term Follow Up (LTFU) Study
- Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC
- Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies
Awards
- 2012 Philadelphia Super Doctors
Treatments
- Brain Tumor
- Acute Myeloid Leukemia (aml)
- Immunodeficiency
- Leukemia
- Dermal Aesthetics
- Extra Corporeal Shockwave Therapy
Dr. Stephan A Grupp M.D.'s Practice location
Practice At
34th & Civic Center Blvd Children's Hospital -Philadelphia, PA 19104Get Direction
Practice At
3401 Civic Center Blvd Children's Hospital -Philadelphia, PA 19104Get Direction
Dr. Stephan A Grupp M.D.'s reviews
Write ReviewPatient Experience with Dr. Grupp
Recommended Articles
![]()
What Should I Know About Blood Clots?Blood flows continuously through blood vessels and supplies nutrients and oxygen to different parts of the body. At the site of an injury, a blood clot prevents excess bleeding. Under normal conditions, blood clots are lifesaving. When the clot is formed as a part of normal repair process in the...
![]()
Dealing with Ulcerative Colitis Flare-UpsUlcerative colitis can really send patients on a life-changing roller coaster ride. And not the good kind of roller coaster.UC can be unpredictable and cause people to experience a range of inconsistent symptoms such as diarrhea, constipation, abdominal pain, bloating, urgency, and more. Not only...
![]()
Potential Causes of LeukopeniaIntroductionA decrease in the number of white blood cells (WBCs) is referred to as leukopenia. There are several causes for leukopenia. It may be due to certain drugs, cancer, radiation and chemotherapy for cancer, stem cell transplant, surgery, steroids, or autoimmune disorders. The immune system...
![]()
PurpuraPurpuraPurpura refers to purple-colored spots that are usually seen on the skin, including mucous membranes and other organs. It is also called skin hemorrhages or blood spots.Purpura is usually recognized when there is pooling of blood under the skin due to ruptured small blood vessels. The size of...
![]()
How Is Leukemia Diagnosed?Leukemia in its early stages may present no signs or symptoms, as these only appear when the leukemia cells have taken over a large number of normal blood cells. A person with leukemia is very lucky indeed if early-stage detection occurs incidentally, through a routine blood test or one done for...
![]()
Study Finds 3% of Pediatric Non-Hodgkin Lymphoma Cases Are Transplant RecipientsLymphoma is a blood cancer that affects both children and adults.Lymphoma begins its growth in the lymphatic white blood cells of the lymph system. This system is a major warrior in fighting off infections and diseases. It is part of the body’s immunity team.The lymph system loops throughout the...
Nearby Providers
![]()
Dr. Sarah Michelman Lo MD3401 CIVIC CENTER BLVD PHILADELPHIA PA 19104![]()
Dr. Michael D Hogarty M.D.3401& Civic Center Blvd Philadelphia PA 19104![]()
Dr. Mortimer Poncz M.D.3401 Civic Center Blvd Philadelphia PA 19104![]()
Dr. Elizabeth Fox MDSouth 34th Street And Civic Center Blvd Philadelphia PA 19104![]()
Dr. Susan R Rheingold M.D.3401 Civic Center Blvd Philadelphia PA 19104![]()
Dr. Stephen P Hunger MD3401 CIVIC CENTER BLVD PHILA PA 19104
Nearest Hospitals
COMANCHE COUNTY HOSPITALl
2ND & FRISCO STREET COLDWATER KS 67029PENN PRESBYTERIAN MEDICAL CENTERl
51 NORTH 39TH STREET PHILADELPHIA PA 19104HAHNEMANN UNIVERSITY HOSPITALl
230 NORTH BROAD STREET PHILADELPHIA PA 19102THOMAS JEFFERSON UNIVERSITY HOSPITALl
111 SOUTH 11TH STREET PHILADELPHIA PA 19107