Dr. Charles Dayrit Lopez M.D.
Oncologist | Medical Oncology
3181 Sw Sam Jackson Park Rd Portland OR, 97239About
In 1990 Dr. Lopez earned his Ph.D. in Cell Biology/Endocrinology and in 1991 his medical degree from the University of California at San Francisco. He received his residency training at the University ...
Education and Training
Univ of Ca, San Francisco, Sch of Med, San Francisco Ca 1991
University of California 1991
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Inhibition of cell death by ribosomal protein L35a.
- Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites.
- Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: correlation with clinical outcome.
- Control of ASPP2/(53BP2L) protein levels by proteasomal degradation modulates p53 apoptotic function.
- The p53 pathway promotes efficient mitochondrial DNA base excision repair in colorectal cancer cells.
- hADA2a and hADA3: new players in beta-catenin signaling.
- E2F1 regulates the base excision repair gene XRCC1 and promotes DNA repair.
- Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds.
- New insights into the expanding complexity of the tumor suppressor ASPP2.
- N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence.
- Attenuated expression of apoptosis stimulating protein of p53-2 (ASPP2) in human acute leukemia is associated with therapy failure.
- Lapatinib and gemcitabine for metastatic pancreatic cancer. A phase II study.
- Chemoradiation for Locally Advanced Unresectable Pancreatic Cancer-What Now?
- ΔN-ASPP2, a novel isoform of the ASPP2 tumor suppressor, promotes cellular survival.
- Phase II open label pilot trial of aprepitant and palonosetron for the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients receiving moderately emetogenic FOLFOX chemotherapy for the treatment of colorectal cancer.
Treatments
- Cancer
- Gastrointestinal Cancer
- Liver Cancer
- Pancreatic Cancer
- Anal Cancer
- Esophageal Cancer
- Colon Cancer
- Bile Duct Cancer
- Stomach Cancer
- Aerolase® Technologies
- Lightpod Neo
Professional Memberships
- Member American Society of Clinical Oncology Basic Mechanisms of Cancer Therapeutics Study Section , U.S. N
Fellowships
- STANFORD UNIV HSP, STANFORD, CA,, Oncology 1995
- Medical Oncology, Stanford University Medical Center 1998
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