Kenneth Ber Margulies MD
Cardiologist | Cardiovascular Disease
3400 Spruce Street Philadelphia PA, 19104About
Dr. Kenneth Margulies is a cardiologist practicing in Philadelphia, PA. Dr. Margulies specializes in diagnosing, monitoring, and treating diseases or conditions of the heart and blood vessels and the cardiovascular system. These conditions include heart attacks, heart murmurs, coronary heart disease, and hypertension. Dr. Margulies also practices preventative medicine, helping patients maintain a heart-healthy life.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- The sarcoplasmic reticulum and the Na+/Ca2+ exchanger both contribute to the Ca2+ transient of failing human ventricular myocytes.
- Ventricular unloading and myocyte recovery: insight gained into the pathophysiology of congestive heart failure.
- Preserved contractile function despite atrophic remodeling in unloaded rat hearts.
- Patients with end-stage congestive heart failure treated with beta-adrenergic receptor antagonists have improved ventricular myocyte calcium regulatory protein abundance.
- Electrophysiological alterations after mechanical circulatory support in patients with advanced cardiac failure.
- Differential regulation of mitogen-activated protein kinases in the failing human heart in response to mechanical unloading.
- Contractile protein abnormalities in failing hearts.
- L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices.
- Modulation of contractility in failing human myocytes by reverse-mode Na/Ca exchange.
- Ca influx via the Na/Ca exchanger maintains sarcoplasmic reticulum Ca content in failing human myocytes.
- Calcium influx via I(NCX) is favored in failing human ventricular myocytes.
- Gender differences in post-infarction hypertrophy in end-stage failing hearts.
- Reversal mechanisms of left ventricular remodeling: lessons from left ventricular assist device experiments.
- Unloading-induced remodeling in the normal and hypertrophic left ventricle.
- Cellular basis of abnormal calcium transients of failing human ventricular myocytes.
Clinical Trials
- Electrogram-Guided Myocardial Advanced Phenotyping
- Subcutaneous Furosemide in Acute Decompensated Heart Failure: The SUBQ-HF Study
- A Study to Evaluate Lung Ultrasound as a Method to Measure Changes in Extravascular Lung Water Induced by Positional Changes (LUPE)
- EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE Study)
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